Early detection of retinal alteration by visible and near-infrared optical co-herence tomography (vnOCT) in a dexamethasone-induced ocular hypertension mouse model
Abstract:Purpose: To apply a novel visible and near-infrared optical coherence tomography (vnOCT) in the dexamethasone-induced ocular hypertension mouse model, and test the capability of four optical markers, peripapillary retinal nerve fiber layer (RNFL) thickness, total retinal blood flow, VN ratio and hemoglobin oxygen saturation (sO2), in detecting retinal ganglion cell (RGC) damage in association with ocular hypertension.Methods: Twelve mice (C57BL/6J) were separated into a control (n=6) and a dexamethasone group … Show more
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