Early detection of oral cancer: Detector lies within

Sarode, Sachin C.; Sarode, Gargi S; Karmarkar, Swarada

doi:10.1016/j.oraloncology.2011.11.018

Cited by 21 publications

(13 citation statements)

References 13 publications

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“…Usually, the slides and tissue blocks are exchanged for second opinion as the pathologist prefers to view the slides in real time, and these clinical practices often lead to diagnostic delay, which could prove critical in cases of malignant lesions [35,36].…”

Section: The "Second Medical Opinion Network" In Histopathologymentioning

confidence: 99%

The “Second Opinion Medical Network”

Palmieri¹

2017

Int J Pathol Clin Res

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The "Second Opinion Medical Network" is a consultation referral web and medical office system recruiting a wide panel of real-time available specialists, to whom any patient affected by any disease or syndrome and not satisfied with the diagnosis or therapy can apply for an individual clinical audit. Due to the physician-patient communication gap, most of the patients usually wander around the medical websites looking for proper answers to their health problems. However, this search often becomes compulsive and obsessive and frequently ambiguous and frustrating. Palmieri, et al. defines this borderline or even pathological behavior as the "Web Babel Syndrome"-psychological imbalance affecting young and elderly patients, often with multiple synchronous diseases receiving by their care givers heterogeneous and misleading informations or advices, as well as, confused, contradictory statements and prescriptions. To deal with this problem, the "Second Opinion Medical Network" aims to be a useful "problem-solving" support revisiting each conflictual diagnostic and therapeutic step and properly re-addressing tailored treatments and prognoses, preventing unnecessary investigations and unhelpful and expensive medical and surgical interventions.The aim of this editorial is to describe the role and benefits of such a medical network in our web connected health care system. KeywordsSecond opinion, Network, Surgery, Cancer, EconomyIn 2002, a survey of 4,530 people in Europe and USA showed that 32% of Europeans and 43% of Americans preferred to use health web sites, sponsored by BBC and Yahoo, for health information [3]. However, the internet sites are often lacking of adequate information concerning disease complications and aftercare [4]. This web-searching behaviour is often continuous, compulsory, somehow obsessive, leading to the "Web Babel Syndrome", defined as a physician-patient communication gap frequently occurring when the patient affected by multiple synchronous pathologies, feeds back heterogeneous and misleading informations and prescriptions with the risk to drop in a confusionary state [5][6][7][8].In 1999, the Institute of Medicine report cited fatal medical errors in some 40,000-98,000 Americans PER year [8] supporting once more the concept that a further consultation or specialistic second opinion may be useful antidote to lethal misdiagnosis [9].The term "second opinion" has been widely reported also in histology [10,11] and pathology (e.g. thyroid pathology) [12][13][14][15][16][17][18][19][20] where the diagnosis is often difficult, misunderstood and strongly based on the healthcare professionals' experience. It has been defined as a qualified, interdisciplinary medical opinion, based on medical evidence, of an experienced medical specialist or a team [21]. An effective and helpful second opinion strategy in various pathologies (e.g. oral pathology) is the use of smartphones and software applications, such as WhatsApp Messenger, a crossplatform mobile messaging application that allows the exchang...

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Section: The "Second Medical Opinion Network" In Histopathologymentioning

confidence: 99%

The “Second Opinion Medical Network”

Palmieri¹

2017

Int J Pathol Clin Res

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“…In an Editorial by Sarode et al the potential role of mouth self-examination has been emphasized as a method for reducing the morbidity and mortality rate of oral cancer (20). In a study in India, using a brochure describing the risk factors of oral cancer and precancer, and also showing the appearance of these lesions by photographs, 247 patients out of 8.000 patients who practiced mouth self-examination reported to the clinics (21).…”

Section: Reducing the Mortality Of Oral Cancer By Detection Oral Cancmentioning

confidence: 99%

Are we able to reduce the mortality and morbidity of oral cancer; some considerations

Waal¹

2013

Med Oral

102

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Oral cancer makes up 1%-2% of all cancers that may arise in the body. The majority of oral cancers consists of squamous cell carcinomas. Oral cancer carries a considerable mortality rate, being mainly dependent on the stage of the disease at admission. Worldwide some 50% of the patients with oral cancer present with advanced disease. There are several ways of trying to diagnose oral cancer in a lower tumor stage, being 1) mass screening or screening in selected patients, 2) reduction of patients’ delay, and 3) reduction of doctors’ delay. Oral cancer population-based screening (“mass screening”) programs do not meet the guidelines for a successful outcome. There may be some benefit when focusing on high-risk groups, such as heavy smokers and heavy drinkers. Reported reasons for patients’ delay range from fear of a diagnosis of cancer, limited accessibility of primary health care, to unawareness of the possibility of malignant oral diseases. Apparently, information campaigns in news programs and TV have little effect on patients’ delay. Mouth self-examination may have some value in reducing patients’ delay. Doctors’ delay includes dentists’ delay and diagnostic delay caused by other medical and dental health care professionals. Doctors’ delay may vary from almost zero days up to more than six months. Usually, morbidity of cancer treatment is measured by quality of life (QoL) questionnaires. In the past decades this topic has drawn a lot of attention worldwide. It is a challenge to decrease the morbidity that is associated with the various treatment modalities that are used in oral cancer without substantially compromising the survival rate. Smoking cessation contributes to reducing the risk of oral cancers, with a 50% reduction in risk within five years. Indeed, risk factor reduction seems to be the most effective tool in an attempt to decrease the morbidity and mortality of oral cancer. Key words:Oral cancer, early diagnosis, quality of life.

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“…7 The prevention and timely recognition of such OPMDs not only favours a decreased rate of oral cancer but also improves the chances of survival in subjects developing oral cancer. 8 The 5-year survival rate of oral cancer has remained persistently at a dismal rate of around 50% despite major advances in its treatment. 9 There has been a continuous effort towards developing novel diagnostic techniques, including new panels of OSSC biomarkers.…”

Section: Introductionmentioning

confidence: 99%

Saliva as a Non-Invasive Diagnostic Medium in Proteomics for Oral Squamous Cell Carcinoma Detection

Buch

Chatra

2019

Int J Med Rev

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Non-invasive diagnostic techniques are essential for the screening of oral cancer to reduce high mortality associated with it. The acknowledgement of various research advancements namely omic research and technological advances in the field of genomes has led to an increased use of saliva collection. Obtaining saliva for diagnosis is simple and non-invasive and is safe for both the health worker and the patient. It also permits easy and cost-effective storage methods. Around 3000 differently expressed proteins and peptides have been identified in various proteomic studies involving saliva, and hence, salivary proteomics is being progressively used for the early diagnosis of numerous diseases such as oral cancer, breast cancer, and several autoimmune disorders, among others. The salivary analysis riding on the recent advancements in technology, can prove to be of much more importance in near future.

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Early detection of oral cancer: Detector lies within

Cited by 21 publications

References 13 publications

The “Second Opinion Medical Network”

The “Second Opinion Medical Network”

Are we able to reduce the mortality and morbidity of oral cancer; some considerations

Saliva as a Non-Invasive Diagnostic Medium in Proteomics for Oral Squamous Cell Carcinoma Detection

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