Early Detection of Nasopharyngeal Carcinoma

Tabuchi, Keiji; Nakayama, Masahiro; Nishimura, Bungo; Hayashi, Kentarō; Hara, Akira

doi:10.1155/2011/638058

Cited by 85 publications

(87 citation statements)

References 65 publications

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“…The treatment also depends on the results of the pathologist´s report, especially after determining the stage of cancer in the patient's body 1 . Furthermore, the greatest benefits provided by histopathological examination is determined of the classification scheme of cancer, which depend on the tumors gross morphology, the degree of cellular differentiation and the tumor´s histogenic or cytogenic origin 1,27 .…”

Section: Resultsmentioning

confidence: 99%

“…In addition to the above benefits that obtain from the histopathological examination, it also provides useful data for epidemiological studies about cancer in any region of the world 27 . The recent results of cancer incidence in only one city (Karbala) in Iraq showed that the GIT organs developed the most common cancers over all periods of study.…”

Section: Resultsmentioning

confidence: 99%

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Does histopathological examination still have value in detecting and preventing cancer?

AL-Janabi¹

2017

BJMHH

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Introduction: Cancer is a very dangerous disease causing a high mortality rate every year. The prevention or reduction of malignant disease required early detection, mainly depending on histological examination as the first step in the diagnosis.Methods: This study was designed to gauge the value of the numbers of histological specimen as an indicator for the level of education to prevent cancer development. Histological specimens of 14670 suspected cases of cancer diseases were histopathologically examined during seven years. Findings: Histopathological examination revealed that 960 patients had a positive result of 38 cancer types, while 13710 patients were clear of any type of cancer. More specimens were received from females, especially in 2014 and the most important organs for diagnosis of cancer, included the gastrointestinal tract (gastro-esophagus, gallbladder, and appendix), skin, lymphoid, and breast.Discussion: Increase the education level about the importance of histopathological examination of any suspected specimens is considered the first step in preventing and controlling the distribution of cancer disease. Some cancer types should receive greater attention in the diagnosis by increased use of the histopathological laboratories.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Does histopathological examination still have value in detecting and preventing cancer?

AL-Janabi¹

2017

BJMHH

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“…A study by Comoretto et al demonstrated that the combined use of MRI and FDG PET-CT had a greater diagnostic accuracy for detecting residual or recurrent disease compared to either modality individually [25]. In addition, PET is reportedly useful for differentiating recurrent NPC tumors from post-radiation changes, such as tissue necrosis, fibrosis and edema [23,[26][27][28][29]. However, in the early postradiation period, FDG uptake can be elevated secondary to inflammation following radiotherapy.…”

Section: Role Of Imagingmentioning

confidence: 99%

Imaging of Nasopharyngeal Carcinoma

Chan

Sahgal

Fatterpekar

et al. 2014

J Nasopharyng Carcinoma

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Nasopharyngeal carcinoma (NPC) is the most common primary neoplasm to arise in the nasopharynx. It is an aggressive tumor with a propensity for local tumour invasion and a high incidence of metastases to cervical lymph nodes. Due to its central location in the nasopharynx, primary tumours have many potential routes of local spread, including into important spaces such as the orbital and intracranial spread. This article discusses the current imaging techniques used in the diagnosis and staging of nasopharyngeal carcinoma, and reviews the 7 th edition of the International Union Against Cancer (UICC) and American Joint Committee on Cancer (AJCC) TMN staging system for nasopharyngeal carcinoma.

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“…5 However, conventional endoscopy has limitation in detecting superficial lesion that makes unnecessary biopsy often happen. 6,7 Narrow Band Imaging is an endoscope technique that uses narrow-band spectrum as a filter to increase the visualization of vascular pattern. Narrow Band Imaging can detect superficial lesion, so that unnecessary biopsy can be reduced.…”

Section: Introductionmentioning

confidence: 99%

Diagnostic Value of Narrow Band Imaging in Diagnosing Nasopharyngeal Carcinoma

Yuniserani¹,

Hernowo²,

Permana³

2017

amj

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Background: Carcinoma is the most common tumor in nasopharynx. Endoscopy is used to determine the presence of lesions suspected of malignancy. Narrow Band Imaging is an endoscopic technique that uses narrow-band spectrum as a filter to determine any mucosal vascular changes in carcinoma. Narrow Band Imaging can early detect superficial mucosal lesions that are difficult to detect with conventional endoscopy, so that diagnosing is more accurate and occurrence of unnecessary biopsies can be reduced. This study aimed to determine diagnostic value of Narrow Band Imaging in diagnosing nasopharyngeal carcinoma. Methods: This diagnostic test study was conducted at Department of Otorhinolaryngology-Head and Neck Surgery Dr. Hasan Sadikin General Hospital, Bandung from September to October 2014. Twenty four patients with clinical signs and symptoms of nasopharyngeal carcinoma that fulfilled the study criteria were assigned using consecutive sampling to examine with Narrow Band Imaging and histopathology examination. The data were then analyzed with 2x2 table to determine sensitivity, specificity, positive predictive value, negative predictive value, and accuracy. Results: In this study, the results of sensitivity, specificity, positive predictive value, negative predictive value, and accuracy in diagnosing nasopharyngeal carcinoma using Narrow Band Imaging were 93.75%, 62.5%, 83.3%, 83.3%, and 83.3%, respectively.

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Early Detection of Nasopharyngeal Carcinoma

Cited by 85 publications

References 65 publications

Does histopathological examination still have value in detecting and preventing cancer?

Does histopathological examination still have value in detecting and preventing cancer?

Imaging of Nasopharyngeal Carcinoma

Diagnostic Value of Narrow Band Imaging in Diagnosing Nasopharyngeal Carcinoma

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