Early Detection of High-grade Biliary Intraepithelial Neoplasia (BilIN-3) in the Cystic Duct Visualized by SpyGlass DS Cholangioscopy

Miyabe, Katsuyuki; Notohara, Kenji; Asano, Go; Jinno, Naruomi; Hori, Yasuki; Yoshida, Michihiro; Naitoh, Itaru; Tsuboi, Koji; Matsuo, Yoichi; Ohara, Hirotaka; Hayashi, Kazuki; Kataoka, Hiromi

doi:10.2169/internalmedicine.5072-20

Cited by 3 publications

(3 citation statements)

References 21 publications

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“…There have been a few reports of cystic duct tumors diagnosed using POCS (23)(24)(25)(26). They described the preoperative diagnosis of stage 0 or I tumors or the diagnosis of advanced cystic duct carcinoma that did not lead to surgery.…”

Section: Discussionmentioning

confidence: 99%

A Preoperative Diagnosis of Advanced Cystic Duct Carcinoma Using SpyGlass DS Cholangioscopy: A Report of Two Cases

et al. 2023

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Primary cystic duct carcinoma is a rare tumor. The curative treatment of cystic duct carcinoma is complete surgical resection, for which the evaluation of local extension is important. We herein report two cases of cystic duct carcinoma in which a preoperative examination was performed using per-oral cholangioscopy (POCS). Both patients underwent POCS due to suspicion of cystic duct carcinoma based on imaging findings. A visual analysis and biopsy were performed to evaluate local extension, which led to surgery. These cases suggest that POCS is useful for the preoperative assessment of local extension in advanced cystic duct carcinoma.

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Section: Discussionmentioning

confidence: 99%

A Preoperative Diagnosis of Advanced Cystic Duct Carcinoma Using SpyGlass DS Cholangioscopy: A Report of Two Cases

et al. 2023

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“…MRCP combined with CA 19-9 every 6–12 months has been shown to have a sensitivity of up to 100% and is a popular surveillance method worldwide, though it currently lacks evidence 11 12. Imaging modalities such as endoscopic ultrasound or endoscopic retrograde cholangiopancreatography have also been described in the detection of cystic duct carcinoma, made more specific when combined with brush cytology 11 13. The latest development would be cholangioscopy (SpyGlass), which has been described in the early detection of HGD (BilIN-3) 9.…”

Section: Discussionmentioning

confidence: 99%

High-grade dysplasia of the cystic duct margin: how should this be managed?

Andersen,

Goh,

Siriwardhane

2023

BMJ Case Rep

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High-grade dysplasia (HGD) in the cystic duct is a rare epithelial lesion that may lead to biliary tract malignancy. Due to its association with aggressive multifocal cholangiocarcinoma, it is important to investigate for concurrent malignancy, remove all areas of HGD and monitor for recurrence or metastasis.We present a case of a woman in her 60s with cholecystitis who underwent a laparoscopic cholecystectomy. On histopathology, the patient was found to have incidental HGD involving the cystic duct margin. After ensuring the absence of concurrent malignancy on cross-sectional imaging, she underwent further resection until the margins were clear of dysplasia. In the absence of clear follow-up guidelines, the patient was closely monitored with outpatient scans for up to 5 years.

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“…They had a good experience with an 84-year-old male patient with epigastralgia. 29 There is no uniform standard for the interpretation of visual impressions gained from POCS of malignant bile duct strictures. It is currently generally accepted that, microscopically, irregular tortuous dilatation of blood vessels, polypoid masses, and fish-egg-like lesions are closely related to malignant tumors.…”

Section: Per-oral Cholangioscopy Used In the Diagnosis Of Biliary Tract Diseasesmentioning

confidence: 99%

The Status and Development of Oral Choledochoscopy Diagnosis and Treatment of Biliary Tract Diseases

Hao¹,

Huang²

2021

IJGM

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Choledochoscopy technology has realized the direct observation of bile duct lesions, and can be loaded with a variety of special accessories to perform the corresponding diagnosis and treatment operations, and has become an important means for the diagnosis of unexplained bile duct stricture and treatment of refractory bile duct stones. With the further enhancement of the imaging quality and operability, the clinical application of choledochoscopy has gradually expanded to the precise positioning of cholangiocarcinoma before surgical resection, the drainage of the gallbladder through the nipple, the removal of the displaced bile duct stent and other fields. This paper briefly reviewed the historical evolution of choledochoscopy and reviewed the latest clinical advances of oral choledochoscopy in the diagnosis and treatment of biliary tract diseases.

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Early Detection of High-grade Biliary Intraepithelial Neoplasia (BilIN-3) in the Cystic Duct Visualized by SpyGlass DS Cholangioscopy

Cited by 3 publications

References 21 publications

A Preoperative Diagnosis of Advanced Cystic Duct Carcinoma Using SpyGlass DS Cholangioscopy: A Report of Two Cases

A Preoperative Diagnosis of Advanced Cystic Duct Carcinoma Using SpyGlass DS Cholangioscopy: A Report of Two Cases

High-grade dysplasia of the cystic duct margin: how should this be managed?

The Status and Development of Oral Choledochoscopy Diagnosis and Treatment of Biliary Tract Diseases

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