Early Detection for Right Ventricular Dysfunction in Bronchopulmonary Dysplasia without Pulmonary Hypertension

Son, Jung–Woo

doi:10.4250/jcu.2016.24.4.268

Cited by 2 publications

(3 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our results are in accord with other studies which have reported abnormal RV function in infants with BPD in the absence of documented elevation in pulmonary artery pressure. 24) …”

Section: Discussionmentioning

confidence: 99%

Right Atrial Strain in Preterm Infants With a History of Bronchopulmonary Dysplasia

Kang

Jung

Hwang

et al. 2022

J Cardiovasc Imaging

View full text Add to dashboard Cite

BACKGROUND Few studies have utilized right atrial (RA) strain to evaluate right ventricular (RV) diastolic dysfunction in preterm infants with bronchopulmonary dysplasia (BPD). We aimed to evaluate the associations of RA strain with BPD severity and respiratory outcomes in preterm infants with BPD. METHODS We retrospectively studied 153 infants with BPD born before 32 weeks of gestational age at CHA Bundang Medical Center. Peak longitudinal right atrial strain (PLRAS) was obtained using velocity vector imaging and compared among infants across BPD severity. Conventional echocardiographic parameters and clinical characteristics were also evaluated. RESULTS In infants with severe BPD, mean gestational age (27.4 ± 2.1 weeks) and mean birth weight (971.3 ± 305.8 g) were significantly smaller than in those with mild BPD (30.0 ± 0.9 weeks, 1,237.3 ± 132.2 g) and moderate BPD (29.6 ± 1.3 weeks, 1,203.2 ± 214.4 g). PLRAS was significantly lower in infants with severe BPD (26.3 ± 10.1%) than in those in the moderate BPD group (32.4 ± 10.9%) or mild BPD group (31.9 ± 8.3%). Tricuspid E/e′ and maximum RA volume index were similar across BPD severity. A decrease in PLRAS was significantly correlated with increased duration of mechanical ventilation duration; however, tricuspid E/e′ and maximum RA volume index were not. CONCLUSIONS Evaluating PLRAS with other parameters in infants with BPD might detect RV diastolic dysfunction. Longer follow-up and larger study populations may elucidate the association between PLRAS and respiratory outcomes in infants with BPD.

show abstract

“…Our results are in accord with other studies which have reported abnormal RV function in infants with BPD in the absence of documented elevation in pulmonary artery pressure. 24) …”

Section: Discussionmentioning

confidence: 99%

Right Atrial Strain in Preterm Infants With a History of Bronchopulmonary Dysplasia

Kang

Jung

Hwang

et al. 2022

J Cardiovasc Imaging

View full text Add to dashboard Cite

show abstract

“…The EI may also have a role in the early identification of abnormal RV pressure load due to PVD, even in the absence of overt PH. An RV pressure load that does not meet criteria for PH has been associated with changes in RV mechanics in BPD 2 as well as increased risk of morbidity and mortality in adult studies. 33–35 In the study by Abraham et al, patients with EIs between 1.15 and 1.29 had a median estimated RV systolic pressure that was 42% of the systemic blood pressure using the modified Bernoulli principle.…”

Section: Discussionmentioning

confidence: 99%

“…1 Poor outcomes may be partially mediated by altered right ventricular (RV) mechanics associated with PVD, even without a formal diagnosis of PH. 2 Screening for abnormalities in RV mechanics has potential utility in understanding disease pathophysiology, prognostication and clinical management of infants with established BPD.…”

mentioning

confidence: 99%

Echocardiographic Measurements of Right Ventricular Mechanics in Infants with Bronchopulmonary Dysplasia at 36 Weeks Postmenstrual Age

Ehrmann

Mourani

Abman

et al. 2018

The Journal of Pediatrics

View full text Add to dashboard Cite

Objective: To test the hypothesis that specific echocardiographic measurements of right ventricle (RV) mechanics at 36 weeks post-menstrual age (PMA) are associated with severity of bronchopulmonary dysplasia (BPD). Study design: A subset of 93 preterm infants (born between 27 and 29 weeks gestation) was retrospectively selected from a prospectively enrolled cohort. BPD was defined using the National Institutes of Health workshop definition, with modifications for oxygen reduction testing and altitude. The cohort was divided into no BPD and BPD using previously published methodology for analyses. Echocardiographic measurements of RV function (tricuspid annular plane systolic excursion, fractional area of change, systolic to diastolic ratio, tissue Doppler myocardial performance index, RV strain), RV remodeling/morphology (end-systolic left ventricular (LV) eccentricity index and RV afterload (pulmonary artery acceleration time measures) were evaluated at 36 weeks PMA. Multivariable logistic regression determined associations between RV measurements and BPD severity. Results: Compared with the no BPD cohort, the BPD group had lower birth weight z-scores (P = .04) and trended toward male predominance (p = 0.08). After adjusting for birth weight z-scores, gestational age and sex, there were no differences in echocardiographic measurements between groups except for the EI (scaled odds ratio (0.1-unit increase) of 1.49 (1.13 – 2.12, p = 0.01). Conclusions: Among conventional and emerging echocardiographic measurements of RV mechanics, EI was the only parameter independently associated with BPD severity in this study. The EI may be a useful echocardiographic measurement to characterize RV mechanics in patients with BPD at 36 weeks PMA.

show abstract

Early Detection for Right Ventricular Dysfunction in Bronchopulmonary Dysplasia without Pulmonary Hypertension

Cited by 2 publications

References 7 publications

Right Atrial Strain in Preterm Infants With a History of Bronchopulmonary Dysplasia

Right Atrial Strain in Preterm Infants With a History of Bronchopulmonary Dysplasia

Echocardiographic Measurements of Right Ventricular Mechanics in Infants with Bronchopulmonary Dysplasia at 36 Weeks Postmenstrual Age

Contact Info

Product

Resources

About