Early CPAP protocol in preterm infants with gestational age between 28 and 32 weeks: experience of a public hospital

Vieira, Bruna S.P.P.; Souza, Thales R.; Paschoal, Luciana N.; Magalhães, M.; Magalhães, Cristiana; Parreira, Verônica Franco

doi:10.1016/j.bjpt.2020.09.001

Cited by 4 publications

(10 citation statements)

References 23 publications

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“…A total of 18 studies were included in the systematic review. These comprised of observational studies without a comparator arm: six studies [29][30][31][32][33][34] , observational studies with a comparator arm: five studies [35][36][37][38][39] and RCTs: seven studies [40][41][42][43][44][45][46] . Eleven (4210 neonates) out of the eighteen studies were synthesized in a meta-analysis.…”

Section: Resultsmentioning

confidence: 99%

“…Eleven (4210 neonates) out of the eighteen studies were synthesized in a meta-analysis. [35][36][37][38][40][41][42][43][44][45][46] The literature search process is given in Figure 1.…”

Section: Resultsmentioning

confidence: 99%

“…DRCPAP was initiated prophylactically in preterm neonates in five studies 33,34,39,40,46 and as a rescue therapy in preterm neonates with varying severity of respiratory distress in eight studies. 29,35,36,38,41,42,44,45 . The various comparator arms evaluated by the included studies were: oxygen supplementation, DRCAP with early INSURE (Intubate SURfactant and Extubate), delayed initiation of DRCPAP after 30 minutes of life, SLI with DRCPAP and surfactant administration followed by invasive mechanical ventilation.…”

Section: Drcpap Care Practicesmentioning

confidence: 99%

“…The type of CPAP devices used varied across the studies with seven studies using a T-piece resuscitator 29,34,40,[42][43][44]46 , four using bubble CPAP 30,33,35,45 and three ventilator CPAP. 36,38,41 Nine of the 18 included studies had used blended oxygen while instituting CPAP therapy. 32,33,34,36,37,38,42,45,46 While eight studies had used a relatively lower fraction of inspired oxygen (FiO2) threshold of 0.3 -0.4 for surfactant administration 29,32,33,34,36,38,42,46 , two studies had used a threshold of ≥ 0.6 41,45 and one study had used only clinical respiratory distress score as a guide for surfactant administration.…”

Section: Drcpap Care Practicesmentioning

confidence: 99%

“…Similarly, Viera et al indicated that only 54% of the eligible very preterm neonates received DRCPAP, while 36% were intubated and 10% received oxygen supplementation. 36 On the contrary, Abelenda et al had showed that after a practice change to using DRCPAP in very preterm VLBW neonates, 95% of the eligible neonates could be stabilized on DRCPAP and transported to the NICU using a CPAP equipped incubator. 35…”

Section: Implementing a Policy Change To Drcpap And Associated Barrie...mentioning

confidence: 99%

See 4 more Smart Citations

Delivery room CPAP in improving outcomes of preterm neonates in low-and middle-income countries: A systematic review and network meta-analysis

et al. 2022

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Section: Resultsmentioning

confidence: 99%

“…Eleven (4210 neonates) out of the eighteen studies were synthesized in a meta-analysis. [35][36][37][38][40][41][42][43][44][45][46] The literature search process is given in Figure 1.…”

Section: Resultsmentioning

confidence: 99%

Section: Drcpap Care Practicesmentioning

confidence: 99%

Section: Drcpap Care Practicesmentioning

confidence: 99%

Section: Implementing a Policy Change To Drcpap And Associated Barrie...mentioning

confidence: 99%

See 3 more Smart Citations

Delivery room CPAP in improving outcomes of preterm neonates in low-and middle-income countries: A systematic review and network meta-analysis

et al. 2022

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Респираторная Поддержка У Недоношенных Детей В Отделении Интенсивной Терапии

et al. 2022

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Во время неонатального перехода аэрация легких имеет решающее значение для изменений дыхательной и сердечно-сосудистой функций, необходимых для выживания. Однако из 130–136 миллионов младенцев, рождающихся ежегодно в мире, примерно 3–5% доношенных детей и 60% недоношенных детей не могут спонтанно проветрить свои легкие и нуждаются в той или иной форме реанимации [1-3]. В большинстве случаев неонатальная «реанимация» включает только обеспечение адекватной вентиляции, что отражает важность и уязвимость младенцев при переходе к легочному газообмену. Как экспериментальные, так и клинические исследования показали, что даже короткие периоды неадекватной респираторной поддержки могут иметь серьезные последствия, приводя к повреждению легких и головного мозга, особенно у недоношенных детей [4].

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Born too soon in a resource-limited setting: A 10-year mixed methods review of a special care baby unit for refugees and migrants on the Myanmar-Thailand border

Hashmi

Darakamon

Aung

et al. 2023

Front. Public Health

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BackgroundPreterm birth is a major public health concern with the largest burden of morbidity and mortality falling within low- and middle-income countries (LMIC).Materials and methodsThis sequential explanatory mixed methods study was conducted in special care baby units (SCBUs) serving migrants and refugees along the Myanmar-Thailand border. It included a retrospective medical records review, qualitative interviews with mothers receiving care within SCBUs, and focus group discussions with health workers. Changes in neonatal mortality and four clinical outcomes were described. A mix of ethnographic phenomenology and implementation frameworks focused on cultural aspects, the lived experience of participants, and implementation outcomes related to SCBU care.ResultsFrom 2008–2017, mortality was reduced by 68% and 53% in very (EGA 28–32 weeks) and moderate (EGA 33–36 weeks) preterm neonates, respectively. Median SCBU stay was longer in very compared to moderate preterm neonates: 35 (IQR 22, 48 days) vs. 10 days (IQR 5, 16). Duration of treatments was also longer in very preterm neonates: nasogastric feeding lasted 82% (IQR 74, 89) vs. 61% (IQR 40, 76) of the stay, and oxygen therapy was used a median of 14 (IQR 7, 27) vs. 2 (IQR 1, 6) days respectively. Nine interviews were conducted with mothers currently receiving care in the SCBU and four focus group discussions with a total of 27 local SCBU staff. Analysis corroborated quantitative analysis of newborn care services in this setting and incorporated pertinent implementation constructs including coverage, acceptability, appropriateness, feasibility, and fidelity. Coverage, acceptability, and appropriateness were often overlapping outcomes of interest highlighting financial issues prior to or while admitted to the SCBU and social issues and support systems adversely impacting SCBU stays. Interview and FGD findings highlight the barriers in this resource-limited setting as they impact the feasibility and fidelity of providing evidence-based SCBU care that often required adaptation to fit the financial and environmental constraints imposed by this setting.DiscussionThis study provides an in-depth look at the nature of providing preterm neonatal interventions in a SCBU for a vulnerable population in a resource-limited setting. These findings support implementation of basic evidence-based interventions for preterm and newborn care globally, particularly in LMICs.

show abstract

Early CPAP protocol in preterm infants with gestational age between 28 and 32 weeks: experience of a public hospital

Cited by 4 publications

References 23 publications

Delivery room CPAP in improving outcomes of preterm neonates in low-and middle-income countries: A systematic review and network meta-analysis

Delivery room CPAP in improving outcomes of preterm neonates in low-and middle-income countries: A systematic review and network meta-analysis

Респираторная Поддержка У Недоношенных Детей В Отделении Интенсивной Терапии

Born too soon in a resource-limited setting: A 10-year mixed methods review of a special care baby unit for refugees and migrants on the Myanmar-Thailand border

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