Early Clinical Evaluation of AcrySof ReSTOR Multifocal Intraocular Lens for Treatment of Cataract

Abstract

Purpose: To evaluate the efficacy, safety and early visual quality of the AcrySof ReSTOR multifocal intraocular lens (IOL) following cataract surgery. Setting: Eye Center of Shandong University of Traditional Chinese Medicine, Jinan Shierming Eye Hospital, Jinan, Shandong, China. Methods:After small-incision phacoemulsification, AcrySof ReSTOR IOLs were implanted in 20 subjects (40 eyes, ReSTOR group). Monofocal IOLs were implanted in 18 subjects (36 eyes, control group). Three to six months following bilateral implantation, visual acuity, depth of focus, corneal astigmatism, contrast sensitivity, glare sensitivity, visual field and spherical aberration were compared between the groups. A subjective outcome questionnaire was also completed by the subjects. Results: Uncorrected near visual acuity 0.5 or better was achieved by 92.5% of the ReSTOR eyes. In the monofocal eyes, only 33.3% of the eyes achieved uncorrected near visual acuity of 0.5 or better. There was no statistical difference between corrected near, distance visual acuity, and uncorrected distance visual acuity in the 2 groups (p > 0.05). In patients with visual acuity 0.5 or better, the depth of focus was 4.87 ± 1.09 and 2.08 ± 0.69 dpt in the ReSTOR and control groups, respectively. The contrast sensitivity, glare sensitivity and visual field of both groups were similar (p > 0.05). The spherical aberration of the 2 groups was similar (t = –0.37, p = 0.71). Visual disturbances were minimal with only 1 patient in each group complaining of glare at night. Conclusion:The AcrySof ReSTOR multifocal IOL is a safe and effective treatment for cataracts.

Double-Pass System (Optical Quality Analysis System) for Analysis of the Multifocal Function of a Diffractive Multifocal Intraocular Lens (Acrysof ReSTOR®) Compared to a Monofocal Intraocular Lens (Acrysof IQ®)

“…In this study, the subjective near visual acuity of the ReSTOR group was better than that of the IQ group like in another study [1][2][3][4][5][6]. However, we could not prove this with objective tools such as OQAS.…”

“…Several studies have evaluated the multifocal function of the ReSTOR by measuring the distance visual acuity and near visual acuity of patients who had cataract surgery with implantation of the lens. [1][2][3][4][5][6] However, they have a weakness in that they depend on the subjective visual acuity of the patients. Recently, Kim et al reported on the testing of the multifocal function of multifocal IOLs including ReSTOR using an optical bench system [7].…”

Comparison of outcomes with multifocal intraocular lenses: a meta-analysis

“…Twenty studies were included in the meta-analysis,19–38 of which 16 were prospective studies (80%) and four were retrospective (Table 1). Eight (50%) of the prospective studies were randomized.…”

Visual field deficits with a multifocal intraocular lens

“…In fact, 1 study showed that the visual field detected with the Octopus 101 autoperimeter was not statistically different between patients with Acrysof Restor multifocal IOLs and monofocal IOLs. 2 Another study, however, demonstrated that as spot intensity and size during visual field testing were decreased, patients with multifocal IOLs experienced a greater decrease in visual field than in phakic patients and those with monofocal IOLs. 3 This may be consistent with the degradation of image quality seen through multifocal IOLs due to reduced contrast sensitivity.…”