Early cleavage of zygotes is indicative of the inherent developmental potential of the cohort.

Miller, K.F.; Sinoway, C.E.; Fry, K.L.; Falcone, T.

doi:10.1016/s0015-0282(01)02369-x

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“…Maternal genes and proteins inherited from the oocyte regulate the first and subsequent cleavages. The state of the ooplasmic organelles such as mitochondria efficiency and adenosine triphosphate concentrations may affect the time of the initial cleavage [18]. Besides, the condition of the zygote may affect the duration of the first cell cycle, which is important in the process of maternal to zygotic transition and zygote genome activation [19].Over all, these findings may indicate that early cleavage is a biologic indicator of fertilization with fitting gametes, which requires a shorter time for the cell cycle.…”

Section: Discussionmentioning

confidence: 99%