Early approval of COVID-19 vaccines: Pros and cons

Rahman, Arifur; Islam, Sayeedul

doi:10.1080/21645515.2021.1944742

Cited by 15 publications

(9 citation statements)

References 100 publications

(129 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The probability of side effects, such as the neurological, articular, and autoimmune effects of vaccines, was reported to be rare. The issue with currently available SARS-CoV-2 vaccines was the absence of an assessment of their long-term side effects, which remain unclear [ 82 ].…”

Section: Current Sars-cov-2 Vaccine Platformsmentioning

confidence: 99%

COVID-19 Genetic Variants and Their Potential Impact in Vaccine Development

Giau

Bagyinszky

2022

Microorganisms

View full text Add to dashboard Cite

In the two years since the SARS-CoV-2 pandemic started, it has caused over 5 million deaths and 400 million infected cases, and the world continues to be on high alert for COVID-19. Among the variants of interest and concern of SARS-CoV-2, the current Omicron (B.1.1.529) and stealth Omicron (BA.2) raised serious concerns due to rapid rates of infection caused by numerous mutations in the spike protein, which could escape from the antibody-mediated neutralization and increase the risk of reinfections. Hence, this work aims to describe the most relevant mutations in the SARS-CoV-2 spike protein, discuss vaccine against variant of concerns, describe rare adverse events after COVID-19 vaccination, introduce the most available promising COVID-19 vaccine candidates, and provide few perspectives of the future variants.

show abstract

Section: Current Sars-cov-2 Vaccine Platformsmentioning

confidence: 99%

COVID-19 Genetic Variants and Their Potential Impact in Vaccine Development

Giau

Bagyinszky

2022

Microorganisms

View full text Add to dashboard Cite

show abstract

“…AstraZeneca, Sinopharm, Moderna, Pfizer, Sputnik V, Convidecia, Janssen. Pelaksanaan program vaksinasi yang dicanangkan oleh pemerintah tidak sedikit menimbulkan pro dan kontra di masyarakat. Pro dan kontra tersebut timbul akibat banyaknya berita yang beredar di publik tentang konspirasi atas tujuan dari diberikannya vaksin kepada seluruh rakyat ( (Rahman & Islam, 2021). Beberapa argument kontra vaksin Covid-19 adalah bahwa vaksin ini dapat memberikan efek samping dan juga kehalalannya.…”

Section: Pendahuluanunclassified

“…Beberapa penelitian terdahulu yang membahas tentang vaksin Covid-19 dan tanggapan masyarakat atas program vaksinasi antara lain Rahman & Islam (2021) yang meneliti tentang "Early approval of COVID-19 vaccines: Pros and Cons" menemukan bahwa oreintasi pembuatan vaksin adalah untuk menangkal adanya virus Covid-19 agar kehidupan masyarakat dapat berjaln kembali secara normal sehingga keberadaan vaksin harus diterima oleh smua kalangan untuk mempercepat normalisasi kehidupan. Saddik et al (2021) meneliti tentang "Determinants of healthcare workers perceptions, acceptance and choice of COVID-19 vaccines: a cross-sectional study from the United Arab Emirates" menjelaskan bahwa vaksin yang paling utama harus diberikan kepada tenaga kesehatan.…”

Section: Journal Of Politicalunclassified

Vaksin dan Sentimen Publik: Sebuah Analisis

Sihidi

Romadhan

Fitrah

et al. 2022

JPI

View full text Add to dashboard Cite

Kajian ini membahas perihal sentimen publik atas kebijakan vaksinasi Covid-19 di Indonesia. Sentimen publik yang terbentuk dikaji melalui informasi yang tersaji di media sosial Twitter dimana terlihat pembelahan yang jelas. Respon publik terbagi menjadi dua yaitu mendukung pelaksanaan program vaksinasi dan menolak vaksinasi. Metode yang digunakan adalah deskriptif kualitatif dengan sumber data utama yang diperoleh melalui Twitter. Sumber data yang diperoleh menjadi alat analisis untuk melihat persepsi publik yang terbentuk antara lain berbasis pada kata kunci tolak vaksin, emotions in text, sentiment valence, dan frequency kata yang dominan. Sumber kajian lain didasarkan pada jurnal penelitian terdahulu yang membahas seputar vaksinasi dan Covid-19. Hasil penelitian menunjukkan bahwa sentimen publik yang terbentuk berkaitan dengan pelaksanaan vaksinasi cenderung positif atau mendukung untuk dijalankan program vaksinasi. Kesimpulan diperoleh melalui dominasi data yang dianalisis dengan kecenderungan utama mendukung arah kebijakan pemerintah. Sentimen positif tersebut sejalan dengan keinginan pemerintah dan publik yang mengharapkan normalisasi kehidupan pasca pandemi Covid-19. Penelitian ini berkontribusi menunjukan media sosial sebagai sarana demokrasi karena terjadi partisipasi publik dalam implementasi kebijakan. Adapun keterbatasan penelitian ini karena durasi pengambilan data yang sangat singkat yakni 12 November -12 Desember 2020 karena keterbatasan limit data kebijakan API twitter, sehingga agar lebih komprehensif dalam merekam sentimen publik perlu memperpanjang waktu penambangan data dan juga menggunakan Social Network Analysis ( SNA) agar peta aktornya lebih terlihat.

show abstract

“…Oxford-AstraZeneca, Pfizer-BioNTech, Sinopharm, Moderna, and Sputnik Janssen) have been used for COVID-19 but they are not available for all people ( 28 – 30 ). Moreover, several studies have already suggested the vaccine escape mutants ( 31 ). The early approval of SARS-CoV-2 vaccines has several limitations ( 31 ).…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, several studies have already suggested the vaccine escape mutants ( 31 ). The early approval of SARS-CoV-2 vaccines has several limitations ( 31 ). It was the first mRNA/DNA vaccine without long term safety data.…”

Section: Introductionmentioning

confidence: 99%

A Review on Measures to Rejuvenate Immune System: Natural Mode of Protection Against Coronavirus Infection

et al. 2022

View full text Add to dashboard Cite

SARS-CoV-2, a novel Corona virus strain, was first detected in Wuhan, China, in December 2019. As of December 16, 2021, almost 4,822,472 people had died and over 236,132,082 were infected with this lethal viral infection. It is believed that the human immune system is thought to play a critical role in the initial phase of infection when the viruses invade the host cells. Although some effective vaccines have already been on the market, researchers and many bio-pharmaceuticals are still working hard to develop a fully functional vaccine or more effective therapeutic agent against the COVID-19. Other efforts, in addition to functional vaccines, can help strengthen the immune system to defeat the corona virus infection. Herein, we have reviewed some of those proven measures, following which a more efficient immune system can be better prepared to fight viral infection. Among these, dietary supplements like- fresh vegetables and fruits offer a plentiful of vitamins and antioxidants, enabling to build of a healthy immune system. While the pharmacologically active components of medicinal plants directly aid in fighting against viral infection, supplementary supplements combined with a healthy diet will assist to regulate the immune system and will prevent viral infection. In addition, some personal habits, like- regular physical exercise, intermittent fasting, and adequate sleep, had also been proven to aid the immune system in becoming an efficient one. Maintaining each of these will strengthen the immune system, allowing innate immunity to become a more defensive and active antagonistic mechanism against corona-virus infection. However, because dietary treatments take longer to produce beneficial effects in adaptive maturation, personalized nutrition cannot be expected to have an immediate impact on the global outbreak.

show abstract

Early approval of COVID-19 vaccines: Pros and cons

Cited by 15 publications

References 100 publications

COVID-19 Genetic Variants and Their Potential Impact in Vaccine Development

COVID-19 Genetic Variants and Their Potential Impact in Vaccine Development

Vaksin dan Sentimen Publik: Sebuah Analisis

A Review on Measures to Rejuvenate Immune System: Natural Mode of Protection Against Coronavirus Infection

Contact Info

Product

Resources

About