Early and Long Period Follow-up Results of Low-Glycemic Index Diet for Migraine Prophylaxis

Evcılı, Gökhan

doi:10.5505/agri.2017.62443

Cited by 34 publications

(38 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The befit was maintained at 90-day. Severity of attacks was reduced at both 30-and 90-day in the drug group but only at 90-day in the diet group [132].…”

Section: Carbohydratementioning

confidence: 85%

Gut-brain Axis and migraine headache: a comprehensive review

et al. 2020

View full text Add to dashboard Cite

The terminology "gut-brain axis "points out a bidirectional relationship between the GI system and the central nervous system (CNS). To date, several researches have shown that migraine is associated with some gastrointestinal (GI) disorders such as Helicobacter pylori (HP) infection, irritable bowel syndrome (IBS), and celiac disease (CD). The present review article aims to discuss the direct and indirect evidence suggesting relationships between migraine and the gut-brain axis. However, the mechanisms explaining how the gut and the brain may interact in patients with migraine are not entirely clear. Studies suggest that this interaction seems to be influenced by multiple factors such as inflammatory mediators (IL-1β, IL-6, IL-8, and TNF-α), gut microbiota profile, neuropeptides and serotonin pathway, stress hormones and nutritional substances. Neuropeptides including CGRP, SP, VIP, NPY are thought to have antimicrobial impact on a variety of the gut bacterial strains and thus speculated to be involved in the bidirectional relationship between the gut and the brain. According to the current knowledge, migraine headache in patients harboring HP might be improved following the bacteria eradication. Migraineurs with long headache history and high headache frequency have a higher chance of being diagnosed with IBS. IBS and migraine share some similarities and can alter gut microflora composition and thereby may affect the gut-brain axis and inflammatory status. Migraine has been also associated with CD and the condition should be searched particularly in patients with migraine with occipital and parieto-occipital calcification at brain neuroimaging. In those patients, gluten-free diet can also be effective in reducing migraine frequency. It has also been proposed that migraine may be improved by dietary approaches with beneficial effects on gut microbiota and gut-brain axis including appropriate consumption of fiber per day, adhering to a low glycemic index diet, supplementation with vitamin D, omega-3 and probiotics as well as weight loss dietary plans for overweight and obese patients.

show abstract

“…The befit was maintained at 90-day. Severity of attacks was reduced at both 30-and 90-day in the drug group but only at 90-day in the diet group [132].…”

Section: Carbohydratementioning

confidence: 85%

Gut-brain Axis and migraine headache: a comprehensive review

et al. 2020

View full text Add to dashboard Cite

show abstract

“…55 An earlier RCT also reported that a high omega-3 and low omega-6 fatty acid diet leads to the reduction of headache days, frequency and pain in people with chronic headaches. 66 Ketogenic 54 and low-glycemic index 50 diets have also been reported to be beneficial in certain people with migraine. 67 The benefit of these diets was expected given that earlier studies have reported a significant correlation between obesity and migraine headache 68,69 and avoiding unhealthy food has led to better outcomes in people with migraine.…”

Section: Discussionmentioning

confidence: 99%

“…The mean frequency and severity of attacks as measured by the visual analog scale (VAS) decreased significantly after 3 months in the diet group compared with those in the medication group (P < .05). 50 In another randomized, cross-over dietary interventional trial, a low-lipid (lipid content <20% of the total daily energy intake) or a normal-lipid (between 25% and 30% of the total daily energy intake) diet was assigned randomly for 3 months and then the diets were crossed over for the following 3 months. A significant correlation between low-lipid diet and decrease in migraine attacks (2.9 ± 3.7; P < .001 vs baseline and P < .05 vs normal-lipid diet) was established.…”

Section: Dietary Risk Factorsmentioning

confidence: 99%

The Role of Diet and Nutrition in Migraine Triggers and Treatment: A Systematic Literature Review

et al. 2020

View full text Add to dashboard Cite

Background.-Migraine is a disabling primary headache disorder often associated with triggers. Diet-related triggers are a common cause of migraine and certain diets have been reported to decrease the frequency of migraine attacks if dietary triggers or patterns are adjusted. Objective.-The systematic literature review was conducted to qualitatively summarize evidence from the published literature regarding the role of diet patterns, diet-related triggers, and diet interventions in people with migraine. Methods.-A literature search was carried out on diet patterns, diet-related triggers, and diet interventions used to treat and/or prevent migraine attacks, using an a priori protocol. MEDLINE and EMBASE databases were searched to identify studies assessing the effect of diet, food, and nutrition in people with migraine aged ≥18 years. Only primary literature sources (randomized controlled trials or observational studies) were included and searches were conducted from January 2000 to March 2019. The NICE checklist was used to assess the quality of the included studies of randomized controlled trials and the Downs and Black checklist was used for the assessment of observational studies. Results.-A total of 43 studies were included in this review, of which 11 assessed diet patterns, 12 assessed diet interventions, and 20 assessed diet-related triggers. The overall quality of evidence was low, as most of the (68%) studies assessing diet patterns and diet-related triggers were cross-sectional studies or patient surveys. The studies regarding diet interventions assessed a variety of diets, such as ketogenic diet, elimination diets, and low-fat diets. Alcohol and caffeine uses were the most common diet patterns and diet-related triggers associated with increased frequency of migraine attacks. Most of the diet interventions, such as low-fat and elimination diets, were related to a decrease in the frequency of migraine attacks. Conclusions.-There is limited high-quality randomized controlled trial data on diet patterns or diet-related triggers. A few small randomized controlled trials have assessed diet interventions in preventing migraine attacks without strong results. Although many patients already reported avoiding personal diet-related triggers in their migraine management, high-quality research is needed to confirm the effect of diet in people with migraine.

show abstract

“…Such finding was also reported in other two clinical trials [ 32 , 33 ]. Furthermore, Evcili et al reported that adherence to a low-glycemic index diet, characterized by a high amount of zinc, resulted in a significant reduction in the frequency of migraine attacks [ 34 ]. In a case-control study, migraine patients had a lower diet quality (defined by Healthy Eating Index) than those without migraine.…”

Section: Discussionmentioning

confidence: 99%

Zinc supplementation affects favorably the frequency of migraine attacks: a double-blind randomized placebo-controlled clinical trial

Ahmadi

Mazloumi-Kiapey

Sadeghi

et al. 2020

Nutr J

View full text Add to dashboard Cite

Background Observational studies have shown a link between zinc deficiency and migraine headaches. We aimed to examine the effect of zinc supplementation on the characteristics of migraine attacks in patients with migraine. Methods This randomized clinical trial was conducted on 80 patients with migraine. Patients were randomly assigned to receive either zinc sulfate (220 mg/d zinc sulfate) or placebo (lactose) for 8 weeks. Anthropometric measures, serum zinc concentrations, and characteristics of migraine attacks (headache severity, frequency and duration of migraine attacks, and headache daily results) were assessed at baseline and end of the trial. Results Compared with the placebo, zinc supplementation resulted in a significant reduction in headache severity (− 1.75 ± 1.79 vs. -0.80 ± 1.57; P = 0.01) and migraine attacks frequency (− 2.55 ± 4.32 vs. -0.42 ± 4.24; P = 0.02) in migraine patients. However, the observed reduction for headache severity became statistically non-significant when the analysis was adjusted for potential confounders and baseline values of headache severity. Other characteristics of migraine attacks including the duration of attacks and headache daily results were not altered following zinc supplementation either before or after controlling for covariates. Conclusion Zinc supplementation had a beneficial effect on the frequency of migraine attacks in migraine patients. Additional well-designed clinical trials with a long period of intervention and different dosages of zinc are required. Trial registration code IRCT20121216011763N23 at www.irct.ir.

show abstract

Early and Long Period Follow-up Results of Low-Glycemic Index Diet for Migraine Prophylaxis

Abstract: The results of the study revealed that low glycemic index diet intake can be an effective and reliable method to reduce migraine attacks.

Cited by 34 publications

References 8 publications

Gut-brain Axis and migraine headache: a comprehensive review

Gut-brain Axis and migraine headache: a comprehensive review

The Role of Diet and Nutrition in Migraine Triggers and Treatment: A Systematic Literature Review

Zinc supplementation affects favorably the frequency of migraine attacks: a double-blind randomized placebo-controlled clinical trial

Contact Info

Product

Resources

About