Early adverse stress and depression severity: A pilot exploration of mediating psychological mechanisms

Gloger, Sergio; Dagnino, Paula; Medina, Dante Diez de

doi:10.1017/s0954579423000688

Cited by 2 publications

(2 citation statements)

References 68 publications

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“…Additional limitations include the exclusion of variables such as emotion regulation. 38 Our analysis focused exclusively on the number of interventions documented in medical records during the observation year. The use of nonparametric analyses limited our ability to demonstrate differences between groups and interactions over time, in contrast to ANOVA.…”

Section: Discussionmentioning

confidence: 99%

Evolution of Depressive Symptoms Among Depression Subtypes of Clinical and Functional Variables in Primary Care in Chile

Vitriol,

Cancino,

Bustamante

et al. 2024

J Prim Care Community Health

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Objective: To compare the evolution of depressive symptoms among depressive subtypes based on clinical and functional variables in a sample of primary care in Chile. Methods: A longitudinal study was conducted in the Maule Region of Chile, focusing on 8 primary care from February 2014 to September 2015. Clinical and functional variables, including Mini International Neuro-psychiatric Interview, Outcome Questionnaire interpersonal and social sub-scales, were applied in a latent class analysis. This analysis categorized 210 patients into 3 subtypes: complex depression (N = 100), recurrent depression (n = 96), and unique depression (n = 14). Complex depression, exhibited a higher probability of suicide attempts, interpersonal and social dysfunction, and association with adverse childhood experiences according the Brief Physical and Sexual Abuse Questionnaire. Patients were monitored over 1 year with the Hamilton scale. The Kruskal-Wallis, non-parametric test, followed by paired Mann-Whitney test evaluated difference in the severity of depressive symptoms between the groups. Additionally, data on mental health interventions were collected. Results: Out of the 210 patients, 89% were women, with a median age of 50 (range 37-58), and 40.1% with only primary education. Sociodemographic characteristics not differ between groups. Significant differences in depressive symptom severity between the groups were found ( X2 90.06, P < .001, Kruskal-Wallis test, η2 = 0.084). Post hoc analyses indicated higher depressive symptoms in complex depression compared to recurrent ( Z = −9.501, P < .001) and unique ( Z = −2.877, P = .004) depression, with no significant difference between recurrent and unique depression ( Z = −1.58, P = .113). There were no differences in the number of medical and psychological controls between the groups. The patients with complex depression required greater modifications in the pharmacological prescriptions than those belonging to the other groups. Conclusion These results provide additional evidence of a complex depression subtype in primary care in Chile associated with adverse childhood experiences, that had worse resolution of depressive symptoms. Contrary to expectations, patients belonging to this group did not receive further medical and psychological interventions, probably due to a lack of specific clinical recommendations.

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Section: Discussionmentioning

confidence: 99%

Evolution of Depressive Symptoms Among Depression Subtypes of Clinical and Functional Variables in Primary Care in Chile

Vitriol,

Cancino,

Bustamante

et al. 2024

J Prim Care Community Health

View full text Add to dashboard Cite

show abstract

“…When children are separated from their parents, they may experience risk for ongoing attachment disruptions [ 14 ] and develop an insecure attachment marked by avoidance or anxious-escalation of their attachment needs [ 20 ]. The insecure attachment is associated with poor mental health outcomes [ 18 ], especially during the COVID-19 pandemic [ 32 ]. It may explain worsening mental health outcomes among those who remained the children experiencing prolonged parent–child separation.…”

Section: Discussionmentioning

confidence: 99%

Immediate and longer-term changes in mental health of children with parent–child separation experiences during the COVID-19 pandemic

Wu,

Wang,

Zhao

et al. 2023

Child Adolesc Psychiatry Ment Health

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Background The psychological impact of the COVID-19 pandemic has been understudied among vulnerable populations. This study aimed to examine the immediate and longer-term changes in the mental health of children with parent–child separation experiences during the COVID-19 pandemic, and identify potential buffering opportunities for mental health. Methods This longitudinal cohort study used data from 723 rural Chinese children who provided data before (Oct. 2019) the COVID-19 pandemic and during the following 2 years. Changes in the probability of depressive symptoms, anxiety symptoms, non-suicide self-injurious (NSSI), suicidal ideation, suicide plan, and suicide attempt were tested across four waves using generalized estimating models (GEE). Results Compared with children who never experienced parent–child separation, children persistently separated from parents since birth experienced greater deterioration in all mental health in the 2-year follow-up (average change: depressive symptoms: β = 0.59, 95% CI [0.26, 0.93]; anxiety symptoms: β = 0.45, 95% CI [0.10, 0.81]; NSSI: β = 0.66, 95% CI [0.31, 1.01]; suicide ideation: β = 0.67, 95% CI [0.38, 0.96]; suicide plan: β = 0.77, 95% CI [0.38, 1.15]; suicide attempt: β = 1.12, 95% CI [0.63, 1.62]). However, children with childhood separation from their parents but reunited with them during the transition to adolescence showed similar even lower changes to counterparts who never experienced parent–child separation (all ps > 0.05). Conclusion These results indicating improvements in supportiveness of the caregiving environment during the transition to adolescence may provide the opportunity to buffer the adverse impact of COVID-19 on mental health. Translating such knowledge to inform intervention and prevention strategies for youths exposed to adversity is a critical goal for the field.

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Early adverse stress and depression severity: A pilot exploration of mediating psychological mechanisms

Cited by 2 publications

References 68 publications

Evolution of Depressive Symptoms Among Depression Subtypes of Clinical and Functional Variables in Primary Care in Chile

Evolution of Depressive Symptoms Among Depression Subtypes of Clinical and Functional Variables in Primary Care in Chile

Immediate and longer-term changes in mental health of children with parent–child separation experiences during the COVID-19 pandemic

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