Earlier Detection of Glaucoma Progression Using High-Density 3-Dimensional Spectral-Domain OCT Optic Nerve Volume Scans

Ratanawongphaibul, Kitiya; Tsikata, Edem; Zemplenyi, Michele; Lee, Hang; Margeta, Milica A.; Ondeck, Courtney; Kim, Janice; Pan, Billy X.; Petrakos, Paul; Coleman, Anne L.; Yu, Fei; Boer, Johannes F. de; Chen, Teresa C.

doi:10.1016/j.ogla.2021.03.010

Cited by 8 publications

(12 citation statements)

References 60 publications

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“…Glaucoma progression analysis was determined separately for the disc photographs, visual fields, RNFL thickness measurements, and MDB thickness measurements using event-based analysis. 18 The first instance each modality showed progression was defined as the date of progression for that modality.…”

Section: Methodsmentioning

confidence: 99%

“… 16 , 26 - 30 These cutoff values were based on past published reports as well as our group’s past publications. 18 , 27 , 29 , 31 The normal rates of aging changes used in this study were −0.5 and −1.0 μ -m/year for RNFL thickness and MDB thickness, respectively. 16 , 32 …”

Section: Methodsmentioning

confidence: 99%

“…16,[26][27][28][29][30] These cut-off values were based on past literature as well as our group's past publications. 18,27,29,31 The normal rates of aging changes used in this study were -0.5 and -1.0 m/year for RNFL thickness and MDB thickness respectively. 16,32 Statistical Analysis Summary data were reported as means ± standard deviation for continuous variables and as counts with percentages for categorical variables.…”

Section: Sd-oct Progression: Rnfl Thinning and Mdb Neuroretinal Rim Thinningmentioning

confidence: 98%

“…17 Furthermore, in a recent prospective study we have demonstrated that MDB thickness measurements detected glaucoma progression 1 to 2 years earlier than disc photos and RNFL thickness measurements. 18 In this study we evaluated open angle glaucoma patients who were followed using four different glaucoma testing modalities [disc photography, Humphrey visual field testing, RNFL thickness measurements, and MDB thickness (i.e. neuroretinal rim thickness in 3D space)] over a 5-year follow-up period.…”

Section: Introductionmentioning

confidence: 99%

“…17 Furthermore, in a recent prospective study, we have demonstrated that MDB thickness measurements detected glaucoma progression 1 to 2 years earlier than disc photos and RNFL thickness measurements. 18 …”

mentioning

confidence: 99%

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Disc Hemorrhages Are Associated With Localized Three-Dimensional Neuroretinal Rim Thickness Progression in Open-Angle Glaucoma

Margeta¹,

Ratanawongphaibul²,

Tsikata³

et al. 2022

American Journal of Ophthalmology

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Sd-oct Progression: Rnfl Thinning and Mdb Neuroretinal Rim Thinningmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

See 3 more Smart Citations

Disc Hemorrhages Are Associated With Localized Three-Dimensional Neuroretinal Rim Thickness Progression in Open-Angle Glaucoma

Margeta¹,

Ratanawongphaibul²,

Tsikata³

et al. 2022

American Journal of Ophthalmology

Self Cite

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An IoT based predictive modeling for Glaucoma detection in optical coherence tomography images using hybrid genetic algorithm

Singh

Pooja

Garg

et al. 2022

Multimed Tools Appl

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Diagnostic value of three-dimensional neuroretinal rim thickness for differentiation of superior segmental optic nerve hypoplasia

Choe,

Jang,

Kim

et al. 2023

Sci Rep

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Little is known about the diagnostic utility of three-dimensional neuroretinal rim thickness (3D-NRRT) for differentiating patients with superior segmental optic nerve hypoplasia (SSOH) from normal-tension glaucoma (NTG). Since SSOH is defined by characteristic optic nerve head features, investigation of diagnostic usefulness of 3D-NRRT is necessary. In this cross-sectional study, 49 SSOH eyes, 52 NTG eyes, and 41 normal eyes were enrolled. Retinal nerve fiber layer thickness (RNFLT) and 3D-NRRT values, as obtained in the right-eye orientation by optical coherence tomography (OCT), were recorded. On RNFLT clock-hour comparison, the 11–3 clock-hour sectors were significantly thinner for SSOH than for NTG (all P < 0.01). As for 3D-NRRT, whereas the 1 and 2 sectors were significantly thinner for SSOH (P < 0.001, P = 0.004), the 6–11 sectors were significantly thinner for NTG (all P < 0.01). The area under receiver operating characteristic (AUROC) curves of the superior and nasal quadrants of RNFLT (0.838, 0.729) were significantly greater than those of 3D-NRRT (0.518, 0.588; P < 0.001, P = 0.043). However, the AUROCs of the inferior and temporal quadrants were significantly greater for 3D-NRRT (0.728, 0.760) than for RNFLT (0.527, 0.550; P = 0.008, P = 0.019). The appropriate use of 3D-NRRT can be useful in differentiating SSOH from NTG.

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Earlier Detection of Glaucoma Progression Using High-Density 3-Dimensional Spectral-Domain OCT Optic Nerve Volume Scans

Cited by 8 publications

References 60 publications

Disc Hemorrhages Are Associated With Localized Three-Dimensional Neuroretinal Rim Thickness Progression in Open-Angle Glaucoma

Disc Hemorrhages Are Associated With Localized Three-Dimensional Neuroretinal Rim Thickness Progression in Open-Angle Glaucoma

An IoT based predictive modeling for Glaucoma detection in optical coherence tomography images using hybrid genetic algorithm

Diagnostic value of three-dimensional neuroretinal rim thickness for differentiation of superior segmental optic nerve hypoplasia

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