Ear, Nose, and Throat Infections

Johnson, Matthew M.

doi:10.1016/b978-0-323-44585-6.00007-2

Cited by 5 publications

(3 citation statements)

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“…Recurrent infection results in CT, where tonsillar hypertrophy leads to respiratory obstruction [ 5 ]. In the present study, the most frequent bacteria were S. aureus and S. oralis ( Table 3 ).…”

Section: Discussionmentioning

confidence: 99%

“…The most commonly isolated bacteria belong to the genera Streptococcus , Neisseria , Haemophilus , Moraxella , Staphylococcus , Corynebacterium , Propionibacterium , Prevotella , and Porphyromonas [ 1 , 2 , 3 ]. Among them, the most common causes of infections are: Streptococcus pneumoniae , S. pyogenes , Haemophilus influenzae , Moraxella catarrhalis , and Staphylococcus aureus [ 3 , 4 , 5 , 6 , 7 ]. The imbalance in the URT microbiota is associated with the increase in the number of invasive pathogenic bacteria, leading to inflammation and infection.…”

Section: Introductionmentioning

confidence: 99%

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Analysis of Tonsil Tissues from Patients Diagnosed with Chronic Tonsillitis—Microbiological Profile, Biofilm-Forming Capacity and Histology

et al. 2022

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Chronic tonsillitis (CT) is a global health issue which can impair patient’s quality of life and has an important socioeconomic impact due to the nonrational use of antibiotics, increased antimicrobial resistance and frequent need for surgical treatment. In order to isolate and identify the causing agents of CT, a total of 79 postoperative palatine and adenoid tissue samples were obtained from the ENT Clinic, KBC Zvezdara, Belgrade, Serbia. Culture identification was performed by MALDI-TOF MS and the Staphylococcus aureus isolates were tested for biofilm forming capability and antibiotic susceptibility. Additionally, a histological examination of palatine and adenoid tissue was performed in order to detect the presence of CT-causing bacteria. The slight majority of participants were females with median age of 28 years for adult patients (group I) and 6 years for children (group II). Analysis of the incidence of bacteria isolated from tissue samples in both groups showed the highest prevalence of S. aureus, Streptococcus oralis and Streptococcus parasanquinis. In addition to interfollicular hyperplasia, colonies of species S. aureus were detected in histological material. The presence of biofilm might be the reason for the recurrence of infection. Therefore, searching for a new treatment of CT is of great importance.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Analysis of Tonsil Tissues from Patients Diagnosed with Chronic Tonsillitis—Microbiological Profile, Biofilm-Forming Capacity and Histology

et al. 2022

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“…2 Symptoms of this condition include sore throat and otalgia on the affected side, trismus, malaise, halitosis and fever. 3 Clinical signs on examination include swelling and erythema of the soft palate on the affected side, with deviation of the uvula to the contralateral side, trismus and cervical lymphadenopathy. Management of a quinsy involves aspiration of the abscess and administration of antibiotics.…”

Section: Introductionmentioning

confidence: 99%

A systematic review of the role of penicillin versus penicillin plus metronidazole in the management of peritonsillar abscess

et al. 2023

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Background Peritonsillar abscess is a localised infection in the peritonsillar space. Pus from the abscess can contain anaerobes. Many clinicians prescribe metronidazole in addition to penicillin, but evidence to support this is limited. This review assessed the evidence of benefit of metronidazole for the treatment of peritonsillar abscess. Methods A systematic review was conducted of the literature and databases including Ovid Medline, Ovid Embase, PubMed and Cochrane library. Search terms included all variations of peritonsillar abscess, penicillin and metronidazole. Results Three randomised, control trials were included. All studies assessed the clinical outcomes after treatment for peritonsillar abscess, including recurrence rate, length of hospital stay and symptom improvement. There was no evidence to suggest additional benefit with metronidazole, with studies suggesting increased side effects. Conclusion Evidence does not support the addition of metronidazole in first-line management of peritonsillar abscess. Further trials to establish optimum dose and duration schedules of oral phenoxymethylpenicillin would benefit clinical practice.

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