Ear Lobe Crease

Koraćević, Goran; Atanaskovic, V.

doi:10.1097/paf.0b013e3181873c48

Cited by 9 publications

(6 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In 2009, Koracevic and Atanaskovic reported their unpublished data from a study which they had conducted 13 years before in Serbia [ 91 ]. They evaluated 78 hospitalized patients (60 men) with mean age 60.4 years.…”

Section: Studies Showing No Association Between Elc and Cadmentioning

confidence: 99%

See 1 more Smart Citation

Ear lobe crease: a marker of coronary artery disease?

Agouridis¹,

Elisaf²,

Nair³

et al. 2015

aoms

View full text Add to dashboard Cite

The ear lobe crease (ELC) has been defined as a deep wrinkle that extends backwards from the tragus to the auricle. It has been proposed that ELC is a predictor of coronary artery disease (CAD). In this review, we consider the possible association between ELC and CAD. Our aim is to systematically address all the relevant evidence in this field. There are many studies that support an association between ELC and CAD. However, other studies did not find such an association. A recent meta-analysis supports the hypothesis that ELC could be a marker of CAD. However, several limitations raise doubts as to whether we should accept this link.

show abstract

Section: Studies Showing No Association Between Elc and Cadmentioning

confidence: 99%

“…They evaluated 78 hospitalized patients (60 men) with mean age 60.4 years. They concluded that whether or not patients had unilateral or bilateral diagonal ELC, or whether the crease was deep or superficial, it did not represent a marker of CAD [ 91 ].…”

Section: Studies Showing No Association Between Elc and Cadmentioning

confidence: 99%

Ear lobe crease: a marker of coronary artery disease?

Agouridis¹,

Elisaf²,

Nair³

et al. 2015

aoms

View full text Add to dashboard Cite

show abstract

“…In 2009 in a letter to the editor in the American Journal of Forensic Medicine and Pathology, Koracevic and Atanaskovic reported on their previously unpublished study which they had conducted 13 years earlier (28). These investigators evaluated 78 unselected hospitalized patients in Nis, Serbia.…”

Section: Evidence Refuting the Relationship Between Coronary Artery Amentioning

confidence: 99%

Diagonal ear lobe crease and atherosclerosis: A review of the medical literature and dental implications

Friedlander¹,

López‐López²,

Ortega³

2012

Med Oral

View full text Add to dashboard Cite

In Spain a significant number of individuals die from atherosclerotic disease of the coronary and carotid arteries without having classic risk factors and prodromal symptoms. The diagonal ear lobe crease (DELC) has been characterized in the medical literature as a surrogate marker which can identify high risk patients having occult atherosclerosis. This topic however has not been examined in either the medical or dental literature emanating from Spain. The majority of clinical, angiography and postmortem reports support the premise that DELC is a valuable extravascular physical sign able to distinguish some patients at risk of succumbing to atherosclerosis of the coronary arteries. A minority of studies have however failed to support this hypothesis. More recently reports using B mode ultrasound have also linked DELC to atherosclerosis of the carotid artery and another report has related DELC to the presence of calcified carotid artery atheromas on panoramic radiographs. DELC is readily visible during head and neck cancer screening examinations. In conjunction with the patient’s medical history, vital signs, and panoramic radiograph, the DELC may assist in atherosclerotic risk assessment. Key words: Diagonal ear lobe crease, atherosclerosis disease, calcified carotid artery, atheromas, panoramic radiographs.

show abstract

“…Despite the above supporting results from different studies, the correlation of DELC and CAD was not demonstrated in several series [18,19]. Koracevic and Atanaskovic [19] reported that irrespective of whether patients had unilateral or bilateral DELC or if the crease was deep or superficial (< 1 mm), there was no significant correlation between DELC and clinical CAD (not even a trend toward significance).…”

Section: Introductionmentioning

confidence: 97%

“…Koracevic and Atanaskovic [19] reported that irrespective of whether patients had unilateral or bilateral DELC or if the crease was deep or superficial (< 1 mm), there was no significant correlation between DELC and clinical CAD (not even a trend toward significance). In a study including 125 consecutive patients in Ireland showed that for the group of patients as a whole, DELC was not significantly related to the presence of CAD [20].…”

Section: Introductionmentioning

confidence: 99%

Diagonal earlobe crease and coronary artery disease in a Chinese population

Yang

Zhao

et al. 2014

BMC Cardiovasc Disord

View full text Add to dashboard Cite

BackgroundMany reports have claimed associations between diagonal earlobe crease (DELC) and coronary artery disease (CAD), but data in Chinese populations are limited.MethodsThis cohort study investigated 449 consecutive Chinese, 250 cases with CAD and 199 without CAD, who were certified by coronary artery angiography in our center. Characteristic differences and the relation of DELC to CAD were assessed by Chi-square and t tests. The multivariate regression was performed to adjust for confounders and ROCs mode were used to detect its predicting performance for CAD.ResultsThe prevalence of DELC was 46.2% in those without CAD and 75.2% in those with CAD (P < .001). Subjects with DELC had more stenostic vessels and higher prevalence of both any and significant coronary artery stenosis than those without DELC (P < .001). The sensitivity, specificity and positive and negative predictive values for DELC to diagnose CAD in the whole population were 0.752, 0.538, 0.671 and 0.633. The higher sensitivity and positive predictive values (ppv) were found in male, the lowest sensitivity and the highest ppv in the <45 years old group, and the lowest specificity and ppv in the >75 years old group. After adjusting for other variables including age, gender and traditional risk factors, DELC remained a positive predictor for CAD (OR, 3.408; 95% CI 2.235-5.196; P < 0.001), but not for hypertension, diabetes mellitus, hypercholesterolemia and hypertriglyceridemia. ROC analysis showed the area under the curve was 0.645 (95% CI 0.593-0.697, p < 0.001).ConclusionsThe study showed a significant association between DELC and CAD independent of established risk factors in Chinese.

show abstract

Ear Lobe Crease

Cited by 9 publications

References 6 publications

Ear lobe crease: a marker of coronary artery disease?

Ear lobe crease: a marker of coronary artery disease?

Diagonal ear lobe crease and atherosclerosis: A review of the medical literature and dental implications

Diagonal earlobe crease and coronary artery disease in a Chinese population

Contact Info

Product

Resources

About