1991
DOI: 10.1073/pnas.88.19.8293
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E1BF is an essential RNA polymerase I transcription factor with an intrinsic protein kinase activity that can modulate rRNA gene transcription.

Abstract: We previously described the purification and characterization of EBF, a rat rRNA gene core promoterbinding factor that consists of two polypeptides of 89 and 79 kDa. When this factor was incubated in the absence of any exogenous protein kinase under conditions optimal for protein phosphorylation, the 79-kDa polypeptide of EjBF was selectively phosphorylated. The labeled phosphate could be removed from the EBF polypeptide by treatment with calf intestinal alkaline phosphatase or potato acid phosphatase.Elution … Show more

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