E-Selectin Is Associated with Daytime and 24-Hour Diastolic Blood Pressure Variability in Type 2 Diabetes

Ciobanu, Dana Mihaela; Bala, Cornelia; Rusu, Adriana; Cismaru, Gabriel; Román, Gabriela

doi:10.3390/biomedicines10020279

Cited by 3 publications

(1 citation statement)

References 65 publications

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“…Current evidence suggests that hypertension is accompanied by a chronic pro-inflammatory state and that inflammation may play a role in both the development of hypertension and end organ damage. Ciobanu et al reported that a high serum E-selectin level, as an inflammatory marker, was associated with daytime and 24 h diastolic BP variability in patients with type 2 diabetes [58]. In Kayıkçıo glu et al's study, the CRP/albumin ratio was found to be significant in predicting non-dipper patients even in normotensive individuals, and inflammation was emphasized [59].…”

Section: Our Findings About Abpmmentioning

confidence: 96%

Time to Change Our Viewpoints to Assess Renal Risks in Patients with Solitary Kidneys beyond Traditional Approaches?

Alp,

Saruhan,

Doğan

et al. 2023

JCM

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Solitary functioning kidney (SFK) can be defined as the absence or hypofunction of a kidney due to acquired or congenital reasons. A congenital solitary functioning kidney (cSFK) is more common than is an acquired one (aSFK) and is characterized by the anatomical absence (agenesis) or hypofunction (hypoplasia; hypodysplasia) of one kidney from birth. Among the acquired causes, the most important is nephrectomy (Nx) (due to the donor, trauma or mass resection). Patients with SFK are at risk for the development of chronic kidney disease (CKD) in the long term. This risk potential is also significantly affected by hypertension. The relationship between hypertension and subclinical chronic inflammation is a connection that has not yet been fully clarified pathogenetically, but there are many studies highlighting this association. In recent years, studies examining different fibrosis and inflammation biomarkers in terms of the evaluation and prediction of renal risks have become increasingly popular in the literature. Oxidative stress is known to play an important role in homocysteine-induced endothelial dysfunction and has been associated with hypertension. In our study, we aimed to investigate the relationship between ambulatory blood pressure monitoring (ABPM) and urinary/serum fibrosis and inflammatory markers in patients with SFK. We prospectively investigated the relationship between ABPM results and soluble urokinase plasminogen activator receptor (suPAR), procollagen type III N-terminal peptide (PIIINP), homocysteine and other variables in 85 patients with SFK and compared them between cSFK and aSFK groups. In the etiology of SFK, a congenital or acquired origin may differ in terms of the significance of biomarkers. In particular, the serum homocysteine level may be associated with different clinical outcomes in patients with cSFK and aSFK.

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Section: Our Findings About Abpmmentioning

confidence: 96%

Time to Change Our Viewpoints to Assess Renal Risks in Patients with Solitary Kidneys beyond Traditional Approaches?

Alp,

Saruhan,

Doğan

et al. 2023

JCM

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Association between napping and 24-hour blood pressure variability among university students: A pilot study

Dai

Wu²,

Jiang³

et al. 2023

Front. Pediatr.

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BackgroundBlood pressure variability (BPV) has been reported to be a predictor of cardiovascular and some cognitive diseases. However, the association between napping and BPV remains unknown. This study aimed to explore the association between napping and BPV.Materials and methodsA cross-sectional study including 105 university students was conducted. Participants’ 24 h ambulatory blood pressure monitoring (24 h ABPM) were measured, and napping behaviors were investigated. BPV were measured by the 24 h ABPM, included standard deviation (SD), coefficient of variation (CV), and average real variability (ARV).ResultsAmong the participants, 61.9% reported daytime napping. We found that nap duration was significantly associated with daytime CV of diastolic blood pressure (DBP) (r = 0.250, P = 0.010), nighttime CV of systolic blood pressure (SBP) (r = 0.217, P = 0.026), 24 h WCV of DBP (r = 0.238, P = 0.014), 24 h ARV of SBP (r = 0.246, P = 0.011) and 24 h ARV of DBP (r = 0.291, P = 0.003). Compared with the no napping group, 24 h WCV of DBP, daytime CV of DBP, and daytime SD of DBP were significantly higher in participants with napping duration >60 min. With multiple regression analysis we found that nap duration was an independent predictor for 24 h ARV of SBP (β = 0.859, 95% CI, 0.101–1.616, P = 0.027) and 24 h ARV of DBP (β = 0.674, 95% CI, 0.173–1.175, P = 0.009).ConclusionsNapping durations are associated with BPV among university students. Especially those with napping durations >60 min had a significantly higher BPV than those non-nappers.

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Amino Acids Metabolomic Signature of Blood Pressure Variability in Type 2 Diabetes

Ciobanu¹

2022

Acta Endo (Buc)

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E-Selectin Is Associated with Daytime and 24-Hour Diastolic Blood Pressure Variability in Type 2 Diabetes

Cited by 3 publications

References 65 publications

Time to Change Our Viewpoints to Assess Renal Risks in Patients with Solitary Kidneys beyond Traditional Approaches?

Time to Change Our Viewpoints to Assess Renal Risks in Patients with Solitary Kidneys beyond Traditional Approaches?

Association between napping and 24-hour blood pressure variability among university students: A pilot study

Amino Acids Metabolomic Signature of Blood Pressure Variability in Type 2 Diabetes

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