E. M. Forster

Abstract

Softcover reprint of the hardcover 1st edition 1987978-0-333-40694-6 All rights reserved. No reproduction, copy or transmission of this publication may be made without written permission.

Alkaline and acidic hydrolysis of the β‐lactam ring

“…A large number of kinetic studies regarding penicillin and cephalosporin degradation in acidic medium are found in the literature [17][18][19]; however, at present, there are still important doubts concerning the reaction pathway [20][21][22].…”

“…Nevertheless, the reactivity of these molecules is essentially different to those of β-lactam antibiotics since oxygen-protonation is thermodynamically favored against nitrogen-protonation [20][21][22][23][24][25], circumstances which, on the other hand, do not take place in β-lactam compounds [19][20][21][22]. There are no theoretical studies on the acidic hydrolysis reaction of the structures selected as models of β-lactam compounds.…”

Imide and isatin derivatives as γ-lactam mimics of ß-lactam antibiotics

“…Hydrolysis of the acyl chlorides with ice water for 3 h. followed by a work-up and trituration using dichloromethane was the best method found for purifying the products. The characteristic methine protons moved downfield to 6.42δ (7), 6.70δ (8) 2 Benzoyl BnON…”

“…1 However, it has been demonstrated that the chemical reactivity of ß-lactams is not unusual and that molecular recognition is as equally important as acylating power. 2 Furthermore non-ß-lactam derivatives such as γ-lactams may show chemical reactivity similar to that of the classical penicillins and cephalosporins 3 and consequently offer the potential to act as inhibitors of the bacterial enzymes.…”

Research on the qEcological Harmonyq Consciousness of Foster's qIndia Tripq

“…"False hypocrisy, philistine reality, indifference and stubbornness, seeking full reproach, cautious, lack of fantasy, these characteristics in any country's middle class will find, but in the United Kingdom they have become a national character." [5] However, this defective national characteristics in the South Asian subcontinentIndia found suitable for the growth of the soil, become add up to grow up. In the novel, through a series of events depicting the British officials and their wife in India has always put a pair of arrogance, indifference, discrimination, exclusion of alien and lack of sympathy for the general attitude.…”