E-cigarettes: Considerations for the otolaryngologist

Biyani, Sneh; Derkay, Craig S.

doi:10.1016/j.ijporl.2015.04.032

Cited by 5 publications

(4 citation statements)

References 23 publications

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“…The concerns with this is the fact that all three of these are carcinogenic compounds and while present in e-cigarettes exist at lesser levels (9-450 times lower) than in tobacco-based cigarettes although nicotine content may be significantly higher in what has been branded a 'risk free' alternative. 15,26 Moreover, the vehicle fluids, for example, propylene glycol and glycerine, have been shown to impair lung function through increased respiratory impedance and can be associated with dry throat and cough and in some cases airway obstruction with an objective reversible reduction in forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) ratio of 3% having been noted upon acute use. Unsurprisingly, this could be more significant in patients who have background COPD/asthma.…”

Section: Safetymentioning

confidence: 99%

“…Prior to this they were freely available from online and market vendors with over 400 brands and >7000 flavours of e-cigarettes now thought to exist each with a very different chemical profile and constitution. 15 As such, clear knowledge of the evidence and toxicology of these agents is required by the responsible clinician, who is likely to encounter their use within patients of different specialities, and in those who wish to stop smoking. 16 It is because of this meteoric rise in popularity of e-cigarettes that as a profession we are playing catch up trying to synthesise evidence regarding an already marketed product.…”

Section: Introductionmentioning

confidence: 99%

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A narrative review evaluating the safety and efficacy of e-cigarettes as a newly marketed smoking cessation tool

Worku

2019

SAGE Open Medicine

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Introduction: E-cigarettes are an alternative to traditional tobacco-based cigarettes. While having considerable societal awareness, conflicting evidence exists to support their claims that they are an effective smoking cessation tool and are safe. Currently >7000 flavours exist with evidence that they exhibit detrimental cellular and tissue effects. A literature review was conducted utilising PubMed and Google Scholar Databases identifying papers between 2014 and 2019. The aims of this study were to accurately gauge the safety and efficacy of e-cigarettes as a smoking cessation tool. Methods: Search terms including ‘electronic cigarettes’ and ‘vaping’ were used to identify suitable references. A total of 314 articles were identified from which papers were excluded due to risk of bias, insufficient detail or were duplicate from which 58 papers were used in the final review. Results: Evidence shows that e-cigarettes can have detrimental effects on several cell lines and animal models with their flavourings and nicotine content implicated; this has, however, not translated into major health outcomes after 3.5 years follow-up but has been linked to chronic lung disease and cardiovascular disease. While advertised as an effective smoking cessation tool, no consensus can be made regarding their effectiveness although the first robust randomised controlled trial reports some success. This, however, is offset by the fact that the most common e-cigarette use is as a dual user and that there is evidence of threefold increased risk of future tobacco smoking. Conclusion: Future research is needed to evaluate the long-term health outcomes and efficacy of e-cigarettes as a smoking cessation tool with greater discussion between patients and clinicians regarding this smoking cessation tool.

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Section: Safetymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A narrative review evaluating the safety and efficacy of e-cigarettes as a newly marketed smoking cessation tool

Worku

2019

SAGE Open Medicine

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“…Significant headway has been made in assessing the effect of e‐cig components on the respiratory and cardiovascular systems, 16 , 17 , 18 , 19 , 20 , 21 , 22 and the number of studies exploring the effects of e‐cigs on other organ systems has also recently grown. 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 …”

mentioning

confidence: 99%

“…On PubMed alone, the number of published articles on e‐cigs has increased from 372 in 2014 to 1132 in 2021 and there are hundreds of review papers on various aspects of e‐cig use. Significant headway has been made in assessing the effect of e‐cig components on the respiratory and cardiovascular systems, 16‐22 and the number of studies exploring the effects of e‐cigs on other organ systems has also recently grown 23‐46 …”

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confidence: 99%

Impact of Electronic Cigarettes on the Upper Aerodigestive Tract: A Comprehensive Review for Otolaryngology Providers

2023

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Objective The use and effects of electronic (e)‐cigarettes (e‐cigs) are particularly relevant for otolaryngology providers as tobacco plays a major role in benign and malignant diseases of the upper aerodigestive tract. This review aims to (1) summarize the recent policies regarding e‐cigs and important patterns of use and (2) serve as a comprehensive resource for clinical providers on the known biologic and clinical effects of e‐cigs on the upper aerodigestive tract. Data Sources PubMed/MEDLINE. Review Methods We conducted a narrative review on (1) general information on e‐cig use and informative findings in the lower respiratory system and a comprehensive review on (2) the effects of e‐cigs on cell and animal models and the clinical implications of these products on human health as is relevant to otolaryngology. Conclusions Although e‐cigs are likely less harmful than conventional cigarettes, preliminary research on e‐cigs suggest several deleterious effects including in the upper aerodigestive tract. Due to this, there has been increased interest in restricting e‐cig usage, particularly among the adolescent population, and caution in recommending e‐cigs to current smokers. Implications for Practice Chronic e‐cig use is likely to have clinical implications. It is critical for otolaryngology providers to be aware of the rapidly changing regulations and use patterns regarding e‐cigs and how e‐cigs influence human health, particularly with regards to the upper aerodigestive tract, to accurately council patients regarding potential risks and benefits of use.

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E-cigarettes: An update on considerations for the otolaryngologist

Biyani

Derkay

2017

International Journal of Pediatric Otorhinolaryngology

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E-cigarettes: Considerations for the otolaryngologist

Cited by 5 publications

References 23 publications

A narrative review evaluating the safety and efficacy of e-cigarettes as a newly marketed smoking cessation tool

A narrative review evaluating the safety and efficacy of e-cigarettes as a newly marketed smoking cessation tool

Impact of Electronic Cigarettes on the Upper Aerodigestive Tract: A Comprehensive Review for Otolaryngology Providers

E-cigarettes: An update on considerations for the otolaryngologist

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