E-2-Benzylidenebenzocycloalkanones III. Studies on transmission of substituent effects on IR carbonyl stretching frequencies and 13C NMR chemical shifts of E-2-(X-benzylidene)-1-indanones. Comparison with the IR data of E-2-(X-benzylidene)-1-indanones, -tetralones, and -benzosuberones

(E)-2-Benzylidenecycloalkanones XII.* Kinetic Measurement of Bovine and Human Serum Albumine Interaction with Selected Chalcones and Their Cyclic Chalcone Analogues by UV Spectrophotometry

“…It is worth mentioning that similar decreasing order of effectiveness of transmission of substituent effects of some para-substituted 1-4 derivatives could be observed by SSP (single substituent parameter) analysis of their IR carbonyl wave numbers [15]. Both methods indicated the strongest conjugation of the most planar structure of compounds 2.…”

Structural studies of seven homoisoflavonoids, six thiohomoisoflavonoids, and four structurally related compounds

“…Earlier we have reported syntheses and 1 H and 13 C NMR spectral data of a systematically substituted (E)-2-benzylidene-1-benzocyclanones [13][14][15][16] and (E)-3-benzylidene-4-chromanones [12]. As a continuation of this series of studies, synthesis of (Z)-3-arylidene-4-thiochromanones (IVa-IVd) is now performed and their stereochemistry compared with the related (E)-3-arylidene-4-chromanones (IIIa-IIIe).…”

“…The 13 C NMR chemical shifts are referenced to the center peak of the solvent CDCl 3 (d = 77.0 ppm from internal TMS). In PFG 1 H, 13 C HMQC, and HMBC measurements the numbers of data points were 1024 (f 2 = 1 H) 9 256 (f 1 = 13 C). This matrix was zero filled to 2048 9 512 and apodized by a shifted sine bell window function along both axes prior to FT.…”

“…The one-dimensional 1 H and 13 C as well as two-dimensional PFG [21] 1 H, 1 H COSY [22,23], PFG 1 H, 13 C HMQC [24,25], and PFG 1 H, 13 C HMBC [26] spectra were recorded for 0.5 M CDCl 3 solution in a 5 mm sample tube at 30°C on a Bruker Avance DRX 500 spectrometer working at 500.13 MHz for 1 H and 125.77 MHz for 13 C, respectively. In 1 H NMR experiments the number of data points was 64 K giving a spectral resolution of 0.05 Hz, the number of scans was 8 and the flip angle 30°.…”

“…In this work 1 H and 13 C NMR chemical shifts are presented for several homoisoflavonoid derivatives of four subgroups: 3-benzyl-2-chromen-4-one (Ia, Ib), 3-benzyl-2-thiochromen-4-one (IIa, IIb), (E)-3-benzylidene-4-chromanone (IIIa-IIIe), (Z)-3-benzylidene-4-thiochromanone (IVa-IVd) and four structurally related compounds: 2-benzyl-1,2,3,4-tetrahydro-1-naphthol (V), 2-benzyl-and (E)-2-benzylidene-1-tetralones (VI, VII), as well as (E)-2-benzylidene-1-benzosuberol (VIII). The obtained NMR data can be related with the electron densities in these molecules [13,14] which further are connected with their biological and physiological activity [12,15,16]. Single crystal X-ray diffraction was attempted for all structures, but only for compounds IIIa-IIId and V-VII the structures were obtained.…”