Dystonic and Dyskinetic Reactions Induced by H1 Antihistaminic Medication

Smith, Robert E.; Domino, Edward F.

doi:10.1007/978-94-011-6381-1_30

Cited by 10 publications

(1 citation statement)

References 13 publications

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“…[30] Other hypothesis include rebound increases in nigral inhibition of the basal ganglia and involvement of the aminobutyric acid neurotransmitter system have been postulated. [30][31][32] Furthermore, apparent life-threatening events have been associated with use of common cold medications. [33] In January 2007, the CDC published a report describing three deaths of infants aged <6 months of age for which cough and cold medications were determined to be the underlying cause of death.…”

Section: Discussionmentioning

confidence: 99%

Prescription practice of antihistamines for acute upper respiratory tract infections in pediatric patients in a local emergency department in Hong Kong

Lui¹

2017

World Journal of Emergency Medicine

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BACKGROUND:Currently there is very limited data in the literature assessing the prevalence of antihistamine prescription, and there is no local prevalence data about the prescription of antihistamine agents among primary practitioner and emergency physicians. The objectives are 1) to report the prevalence of antihistamine prescription for children less than 6 years old with acute upper respiratory infection and 2) to explore the associated factors for the prescription practice.METHODS: This is a cross-sectional study. All consecutive cases of paediatric patients aged 6 or below who presented to the emergency department during a study period of one week from April 1 to July 4, 2009 with diagnosis of acute upper respiratory infection were included. Totally 162 patients were included. RESULTS:Among the 162 cases, 141 (87%) patients were prescribed one antihistamine of any group. Sixty (37%) patients were prescribed two or more antihistamines. In multivariate logistic regression model, age was found to be signifi cantly (P<0.001) associated with multiple antihistamine prescription (OR=1.042, 95%CI=1.02 to 1.06). Years of graduation of attending physician for more than 5 years was also a strong predictor of multiple antihistamine prescription (OR=4.654, 95%CI=2.20 to 9.84, P<0.001). CONCLUSION:In the local emergency department, patients' age and the years of graduation from medical school of the attending physician were predictors of multiple antihistamine prescription for acute upper respiratory infections for children aged less than 6.

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Section: Discussionmentioning

confidence: 99%