Dysthyroid Optic Neuropathy

Orbital decompression in endocrine exophthalmos of Graves' disease

“…Optic neuropathy indicated by a decrease in the visual acuity is an important complication (Gorman 1978;Trobe et al 1978;Trobe 1981). The reason is probably pressure of the muscle cone on the optic nerve which is visualized on computerized tomography (Enzmann et al 1976).…”

“…Because of this pathogenesis orbital decompression would seem to be a logical approach and good results are indeed obtained with this method (Gorman et al 1974;Panzo & Tomsak 1983). Good results have also been reported with glucocorticoids (Trobe et al 1978;Panzo & Tomsak 1983) and retrobulbar irradiation (Kriss et al 1975) but relapses occur. Amelioration of the visual acuity occurred in 7 eyes of the 6 patients with optic neuropathy in the present material.…”

Orbital decompression in endocrine exophthalmos of Graves' disease

“…Optic neuropathy indicated by a decrease in the visual acuity is an important complication (Gorman 1978;Trobe et al 1978;Trobe 1981). The reason is probably pressure of the muscle cone on the optic nerve which is visualized on computerized tomography (Enzmann et al 1976).…”

“…Because of this pathogenesis orbital decompression would seem to be a logical approach and good results are indeed obtained with this method (Gorman et al 1974;Panzo & Tomsak 1983). Good results have also been reported with glucocorticoids (Trobe et al 1978;Panzo & Tomsak 1983) and retrobulbar irradiation (Kriss et al 1975) but relapses occur. Amelioration of the visual acuity occurred in 7 eyes of the 6 patients with optic neuropathy in the present material.…”

Orbital Decompression for Preservation of Vision in Graves' Ophthalmopathy

“…The incidence of exophthalmos in patients with hyperthyroid disease ranges from 40% to 75% but fortunately only 2% to 5% of these patients have develop¬ ment of optic nerve involvement with loss of vision. [1][2] The clinical course of Graves' ophthalmopathy may be completely independent from the clinical course of the as¬ sociated thyroid disease. In fact, the eye disease may occur long after the thyroid disease has been appropriately treated.…”

“…Transantral decompression of the orbit offers a safe and effective therapeutic modality for vision-threatening Graves' ophthalmopathy. ( Graves' disease is a multisystem disorder of unknown etiology that is characterized by one or more of the following: (1) hyperthyroidism associated with diffuse hyperplasia of the thyroid gland, (2) infiltrative ophthal¬ mopathy, and (3) infiltrative dermopathy (localized pretibial myxedema). The incidence of exophthalmos in patients with hyperthyroid disease ranges from 40% to 75% but fortunately only 2% to 5% of these patients have develop¬ ment of optic nerve involvement with loss of vision.…”

CT Scanning in Diagnosis of Orbital Disease

“…The massive enlargement of the ocular muscles in the apex of the orbit confirms the compressive nature of the optic neuropathy and visual loss (Trobe et al 1978). It also emphasizes the need for any decompression to involve the orbital apex in order to be effective.…”

Orbital decompression in endocrine exophthalmos of Graves' disease

“…Optic neuropathy indicated by a decrease in the visual acuity is an important complication (Gorman 1978;Trobe et al 1978;Trobe 1981). The reason is probably pressure of the muscle cone on the optic nerve which is visualized on computerized tomography (Enzmann et al 1976).…”

“…Because of this pathogenesis orbital decompression would seem to be a logical approach and good results are indeed obtained with this method (Gorman et al 1974;Panzo & Tomsak 1983). Good results have also been reported with glucocorticoids (Trobe et al 1978;Panzo & Tomsak 1983) and retrobulbar irradiation (Kriss et al 1975) but relapses occur. Amelioration of the visual acuity occurred in 7 eyes of the 6 patients with optic neuropathy in the present material.…”

Orbital Decompression for Preservation of Vision in Graves' Ophthalmopathy

“…The incidence of exophthalmos in patients with hyperthyroid disease ranges from 40% to 75% but fortunately only 2% to 5% of these patients have develop¬ ment of optic nerve involvement with loss of vision. [1][2] The clinical course of Graves' ophthalmopathy may be completely independent from the clinical course of the as¬ sociated thyroid disease. In fact, the eye disease may occur long after the thyroid disease has been appropriately treated.…”

“…Transantral decompression of the orbit offers a safe and effective therapeutic modality for vision-threatening Graves' ophthalmopathy. ( Graves' disease is a multisystem disorder of unknown etiology that is characterized by one or more of the following: (1) hyperthyroidism associated with diffuse hyperplasia of the thyroid gland, (2) infiltrative ophthal¬ mopathy, and (3) infiltrative dermopathy (localized pretibial myxedema). The incidence of exophthalmos in patients with hyperthyroid disease ranges from 40% to 75% but fortunately only 2% to 5% of these patients have develop¬ ment of optic nerve involvement with loss of vision.…”

CT Scanning in Diagnosis of Orbital Disease

“…The massive enlargement of the ocular muscles in the apex of the orbit confirms the compressive nature of the optic neuropathy and visual loss (Trobe et al 1978). It also emphasizes the need for any decompression to involve the orbital apex in order to be effective.…”

Orbital decompression in endocrine exophthalmos of Graves' disease

“…Optic neuropathy indicated by a decrease in the visual acuity is an important complication (Gorman 1978;Trobe et al 1978;Trobe 1981). The reason is probably pressure of the muscle cone on the optic nerve which is visualized on computerized tomography (Enzmann et al 1976).…”

“…Because of this pathogenesis orbital decompression would seem to be a logical approach and good results are indeed obtained with this method (Gorman et al 1974;Panzo & Tomsak 1983). Good results have also been reported with glucocorticoids (Trobe et al 1978;Panzo & Tomsak 1983) and retrobulbar irradiation (Kriss et al 1975) but relapses occur. Amelioration of the visual acuity occurred in 7 eyes of the 6 patients with optic neuropathy in the present material.…”

Orbital Decompression for Preservation of Vision in Graves' Ophthalmopathy

“…The incidence of exophthalmos in patients with hyperthyroid disease ranges from 40% to 75% but fortunately only 2% to 5% of these patients have develop¬ ment of optic nerve involvement with loss of vision. [1][2] The clinical course of Graves' ophthalmopathy may be completely independent from the clinical course of the as¬ sociated thyroid disease. In fact, the eye disease may occur long after the thyroid disease has been appropriately treated.…”

“…Transantral decompression of the orbit offers a safe and effective therapeutic modality for vision-threatening Graves' ophthalmopathy. ( Graves' disease is a multisystem disorder of unknown etiology that is characterized by one or more of the following: (1) hyperthyroidism associated with diffuse hyperplasia of the thyroid gland, (2) infiltrative ophthal¬ mopathy, and (3) infiltrative dermopathy (localized pretibial myxedema). The incidence of exophthalmos in patients with hyperthyroid disease ranges from 40% to 75% but fortunately only 2% to 5% of these patients have develop¬ ment of optic nerve involvement with loss of vision.…”

CT Scanning in Diagnosis of Orbital Disease

“…The massive enlargement of the ocular muscles in the apex of the orbit confirms the compressive nature of the optic neuropathy and visual loss (Trobe et al 1978). It also emphasizes the need for any decompression to involve the orbital apex in order to be effective.…”