“…As redox levels in cells are tightly correlated to the induction of ferroptosis, several important players in regulating GSH levels, GPX4, SLC3A2, and SCL7A11 are critical players in ferroptosis. − Additionally, several enzymes involved in fatty acid synthesis such as stearoyl CoA desaturase (SCD)-1 and fatty acid desaturases (FADS1 and FADS2), play important roles in the synthesis of PUFAs . Therefore, cancer cells with higher levels of SCD1 and FADS1/FADS2 are prone to undergo ferroptosis. − …”