Dyspnea, Dysphonia, and Cough

Nielsen, Skyler W.; Stevens, Jayne R.; Dion, Gregory R.; Howard, N. Scott

doi:10.1177/0003489415586845

Cited by 11 publications

(5 citation statements)

References 15 publications

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“…TPO is a rare, benign condition that is assumed to be underdiagnosed due to the wide variation of nonspecific symptoms, and that it is usually diagnosed as an incidental finding of imaging ( 1 ). In the presented case, the patient reported atypical dyspnea on exertion but denied other symptoms or histories associated with TPO, such as hemoptysis or recurrent respiratory infection ( 8 ). She has a medical history of GERD, which has been reported in 14% of TPO cases, but PFTs were normal unlike a majority of cases ( 9 ).…”

Section: Discussionmentioning

confidence: 88%

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Tracheopathia osteochondroplastica: a case report illustrating the importance of imaging in this rare disorder

Lauinger,

Yu-Ballard

2024

AME Case Rep

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Background Tracheopathia osteochondroplastica (TPO) is an uncommon and benign abnormality of the cartilaginous tracheal wall. It is characterized by multiple calcified nodules in the submucosa of the trachea and main bronchi. This disorder can present as a wide range of nonspecific symptoms; therefore, TPO is usually found as an incidental finding during bronchoscopy. However, it does pose a risk for complicated intubations and recurrent respiratory infection. The etiology of the disease is unknown, and treatments are often only for symptomatic relief, if necessary. Case Description In this report, we present a case of a 71-year-old woman who presents with chest pain and dyspnea on exertion. She has a history of takotsubo cardiomyopathy, and the symptoms have been persistent since the diagnosis over 6 months ago. A chest computed tomography (CT) demonstrated possible endobronchial lesions and minimal fibrosis. A bronchoscopy was completed following this observation, and it revealed nodular lesions on the cartilaginous rings of the trachea. She was diagnosed with TPO. The patient also has a history of gastroesophageal reflux disease (GERD) and reports relief from chest pain and dyspnea post-esophageal dilation for dysphagia. Conclusions This case illustrates the relationship between esophageal, cardiac, and pulmonary symptoms, and highlights the role of imaging in the diagnosis of TPO. It also demonstrates a possible treatment option for symptomatic TPO that hasn’t previously been discussed.

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Section: Discussionmentioning

confidence: 88%

“…However, cases have been identified in both younger and older individuals with and without history of tobacco use ( 6 ). TPO has been reported in coexistence with thyroid pathologies and malignancies ( 7 , 8 ). The variation in disease presentation, severity, and course supports thorough investigation of clinical cases involving TPO.…”

Section: Introductionmentioning

confidence: 99%

Tracheopathia osteochondroplastica: a case report illustrating the importance of imaging in this rare disorder

Lauinger,

Yu-Ballard

2024

AME Case Rep

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“…En nuestros casos con traqueobroncopatía osteocondroplástica, los síntomas relacionados que se identificaron fueron tos crónica, disnea de esfuerzo, disfonía, carraspera y prurito faríngeo. La tos crónica fue el síntoma más común, similar a lo reportado en otros trabajos [24][25][26][27][28][29]. No encontramos ningún vínculo entre la traqueobroncopatía osteocondroplástica y otras enfermedades inflamatorias respiratorias, tampoco encontramos ningún antecedente familiar en nuestro estudio, lo que es similar a lo reportado en otros trabajos [25].…”

Section: Discussionunclassified

Osteochondroplastic tracheobronchopathy: Four case reports

Rodríguez Hidalgo,

Cribillero Meza,

Ruíz Caballero

et al. 2024

Medwave

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Introduction Osteochondroplastic tracheobronchopathy is a rare benign chronic disease of unknown etiology. Bronchoscopy remains the gold standard for diagnosing osteochondroplastic tracheobronchopathy. Its typical findings are described as a cobblestone, rock garden, mountainscape, or stalactite cave appearance. The present work aims to show the main clinical features of this rare pathology. Clinical cases The clinical data of four middle-aged patients, three men and one woman, were analyzed. The main clinical symptoms were chronic cough, dyspnea, and dysphonia. The patient's preliminary diagnosis was made by computed axial tomography of the chest, confirmed by bronchoscopy and histopathological examination. Treatment included medication for symptoms and, in one case, cryosurgery and argon plasma coagulation. Discussion Diagnosing osteochondroplastic tracheobronchopathy was not easy, given its uncommon nature and non-specific symptoms often found in other pathologies. No case series articles on this pathology have been published in Peru. Therefore, we used the original articles published in other countries to reference our findings. Conclusion Osteochondroplastic tracheopathy is a benign disease that typically affects adults. Men are more likely to be affected. Its clinical manifestations are non-specific and frequently of pharyngeal origin, and the cause is not yet defined. Chest computed axial tomography combined with bronchoscopy are the main diagnostic procedures. There is no standard treatment with consistent therapeutic effects.

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“…The administration of anti-infective treatment, drainage of airway secretions, inhalation of bronchodilators, and administration of corticosteroids may alleviate the symptoms. 13 For some patients, long-term clinical observation may be a good choice. 14 Endoscopic interventional excision can be used to relieve clinical symptoms, but studies with larger sample sizes are warranted to validate these measures.…”

Section: Discussionmentioning

confidence: 99%

Multi-Nodule of Large Airway: Tracheobronchopathia Osteochondroplastica, Two Cases Report and Literature Review

Jiang¹,

Yang²,

Guo

2021

Ear Nose Throat J

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We report two subjects with tracheobronchopathia osteochondroplastica (TO), including the clinical manifestations, histological findings, and clinical treatments, which were analyzed retrospectively. One patient with TO was a 60-year-old woman, and the other was a 47-year-old man. The main clinical manifestations were cough, chest pain, and dyspnea. Computed tomography (CT) images showed that TO mainly occurred in the trachea and main bronchus. Histological analysis showed inflammatory exudation, squamous metaplasia, submucosal cartilaginous, and ossification. We present the two cases to increase physician and patient awareness of this benign disease and to improve their understanding of the disease manifestations and potential complications.

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Dyspnea, Dysphonia, and Cough

Abstract: While TPO may be a rare diagnosis in the general otolaryngologist practice, symptoms frequently bring patients into the otolaryngologist's clinic, and an awareness of the disease can help minimize unnecessary interventions and allow the surgeon to appropriately counsel patients.

Cited by 11 publications

References 15 publications

Tracheopathia osteochondroplastica: a case report illustrating the importance of imaging in this rare disorder

Tracheopathia osteochondroplastica: a case report illustrating the importance of imaging in this rare disorder

Osteochondroplastic tracheobronchopathy: Four case reports

Multi-Nodule of Large Airway: Tracheobronchopathia Osteochondroplastica, Two Cases Report and Literature Review

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