Abstract:Schizophrenia is a devastating disease that affects at least 1% of humanity. Current understanding is focused on two different hypotheses: excessive dopamine and excessive pruning. Both hypotheses are not totally compliant with observations and are inadequate to provide a unifying framework that explains the cause, mechanism, and symptoms. In this hypothetical work, we propose a unifying hypothesis of schizophrenia. The proposed dysmodulation occurs as a result of growth factor deficiency and any impairment i… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.