Dyskinesia in Treatment-Naive and Stimulant-Treated Children With ADHD

Keresztény, Ágnes; Ferenczi-Dallos, Gyöngyvér; Velö, Szabina; Gádoros, Júlia; Balázs, Judit

doi:10.1177/1087054716679262

Cited by 2 publications

(2 citation statements)

References 45 publications

(91 reference statements)

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“…However, a single dose of methylphenidate did not alter the AIMS score. Keresztény et al [ 51 ] compared three groups: drug-naïve ADHD, stimulant treatment, and healthy controls. The ADHD group treated with methylphenidate had a higher AIMS score than the other two groups, and dyskinesia was mainly observed in the orofacial area and upper extremities.…”

Section: Stereotypies and Other Movement Disordersmentioning

confidence: 99%

Stimulant Induced Movement Disorders in Attention Deficit Hyperactivity Disorder

Nam

Lee

Park

2022

J Korean Acad Child Adolesc Psychiatry

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Stimulants, such as amphetamine and methylphenidate, are one of the most effective treatment modalities for attention deficit hyperactivity disorder (ADHD) and may cause various movement disorders. This review discusses various movement disorders related to stimulant use in the treatment of ADHD. We reviewed the current knowledge on various movement disorders that may be related to the therapeutic use of stimulants in patients with ADHD. Recent findings suggest that the use of stimulants and the onset/aggravation of tics are more likely to be coincidental. In rare cases, stimulants may cause stereotypies, chorea, and dyskinesia, in addition to tics. Some epidemiological studies have suggested that stimulants used for the treatment of ADHD may cause Parkinson’s disease (PD) after adulthood. However, there is still a lack of evidence that the use of stimulants in patients with ADHD may cause PD, and related studies are only in the early stages. As stimulants are one of the most commonly used medications in children and adolescents, close observations and studies are necessary to assess the effects of stimulants on various movement disorders, including tic disorders and Parkinson’s disease.

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Section: Stereotypies and Other Movement Disordersmentioning

confidence: 99%

Stimulant Induced Movement Disorders in Attention Deficit Hyperactivity Disorder

Nam

Lee

Park

2022

J Korean Acad Child Adolesc Psychiatry

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“…In addition, ADRs have been reported after exposure to methylphenidate or other psychostimulants in children treated with (or shortly after the withdrawal of) DRBA [ 146 , 147 , 148 ], suggesting that dopaminergic drugs may increase the risk of ADRs in patients exposed to DRBA. Nevertheless, methylphenidate may cause several dyskinetic reactions, including focal dystonia, also in DRBA-naïve patients [ 149 , 150 , 151 , 152 , 153 ]. Treatment with anticholinergic drugs may be beneficial [ 141 ].…”

Section: Drug-induced and Toxic Movement Disordersmentioning

confidence: 99%

Acute Movement Disorders in Childhood

Garone

Graziola

Grasso

et al. 2021

JCM

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Acute-onset movement disorders (MDs) are an increasingly recognized neurological emergency in both adults and children. The spectrum of possible causes is wide, and diagnostic work-up is challenging. In their acute presentation, MDs may represent the prominent symptom or an important diagnostic clue in a broader constellation of neurological and extraneurological signs. The diagnostic approach relies on the definition of the overall clinical syndrome and on the recognition of the prominent MD phenomenology. The recognition of the underlying disorder is crucial since many causes are treatable. In this review, we summarize common and uncommon causes of acute-onset movement disorders, focusing on clinical presentation and appropriate diagnostic investigations. Both acquired (immune-mediated, infectious, vascular, toxic, metabolic) and genetic disorders causing acute MDs are reviewed, in order to provide a useful clinician’s guide to this expanding field of pediatric neurology.

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Dyskinesia in Treatment-Naive and Stimulant-Treated Children With ADHD

Abstract: These results call attention that clinicians should take special care for the possible development of dyskinesia during the treatment of their ADHD patients with methylphenidate.

Cited by 2 publications

References 45 publications

Stimulant Induced Movement Disorders in Attention Deficit Hyperactivity Disorder

Stimulant Induced Movement Disorders in Attention Deficit Hyperactivity Disorder

Acute Movement Disorders in Childhood

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