Dyskinesia Associated with Oral Phenobarbital Administration in a Dog

Kube, Stephanie A.; Vernau, Karen M.; Lecouteur, Richard A

doi:10.1111/j.1939-1676.2006.tb00730.x

Cited by 27 publications

(16 citation statements)

References 9 publications

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“…4 The dog showed progressive twitching of the facial, neck, and shoulder muscles, impairing its ability to walk and worsening as the dose of phenobarbital increased. EEG evaluation during an episode was normal and withdrawal of phenobarbital resulted in complete resolution of the signs.…”

Section: Phenobarbital-induced Dyskinesiamentioning

confidence: 99%

“…3 This review focuses on the primary PDs, in which patients are normal between episodes; however, it is important to note that an example of a secondary dyskinesia has been described in veterinary patients. 4 In humans, classification of PDs has evolved over time. Initially, they were described by their clinical signs, leading to terms such as paroxysmal choreoathetosis.…”

Section: Introductionmentioning

confidence: 99%

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Canine Paroxysmal Movement Disorders

Urkasemsin

Olby

2014

Veterinary Clinics of North America: Small Animal Practice

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Section: Phenobarbital-induced Dyskinesiamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Canine Paroxysmal Movement Disorders

Urkasemsin

Olby

2014

Veterinary Clinics of North America: Small Animal Practice

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“…However, pronounced inter-individual differences exist in the susceptibility to respective effects. Sedation or apathy and other behavioral alterations as well as a disturbance of motor function [ 35 , 36 ], sleep patterns, and cognition [ 37 ] are among the dose-dependent central nervous system effects, which should be considered in a patient’s evaluation. In addition, systemic effects need to be assessed including gastrointestinal effects.…”

Section: Assessment Of Outcome In Individual Patientsmentioning

confidence: 99%

International veterinary epilepsy task force consensus proposal: outcome of therapeutic interventions in canine and feline epilepsy

Potschka

Fischer²,

Löscher³

et al. 2015

BMC Vet Res

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Common criteria for the diagnosis of drug resistance and the assessment of outcome are needed urgently as a prerequisite for standardized evaluation and reporting of individual therapeutic responses in canine epilepsy. Thus, we provide a proposal for the definition of drug resistance and partial therapeutic success in canine patients with epilepsy. This consensus statement also suggests a list of factors and aspects of outcome, which should be considered in addition to the impact on seizures. Moreover, these expert recommendations discuss criteria which determine the validity and informative value of a therapeutic trial in an individual patient and also suggest the application of individual outcome criteria. Agreement on common guidelines does not only render a basis for future optimization of individual patient management, but is also a presupposition for the design and implementation of clinical studies with highly standardized inclusion and exclusion criteria. Respective standardization will improve the comparability of findings from different studies and renders an improved basis for multicenter studies. Therefore, this proposal provides an in-depth discussion of the implications of outcome criteria for clinical studies. In particular ethical aspects and the different options for study design and application of individual patient-centered outcome criteria are considered.

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“…(3) Secondary causes -Previous reports exist of PDs which occurred as a result of phenobarbital administration (Kube et al 2006), or following the use of propofol (Mitek et al 2013). As of yet, no definitive genetic cause has been identified in these breeds, which can be directly linked to PDs.…”

Section: Classificationmentioning

confidence: 99%

“…PDs may be triggered by stress, exercise or excitement. There are also reports of drug-induced PDs (Kube et al 2006;Mitek et al 2013). The remainder of this article will largely concern primary PDs.…”

Section: Introductionmentioning

confidence: 99%

Approach to canine paroxysmal dyskinesias

Posporis

Wyatt

Wessmann³

2018

Companion Animal

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The term ‘paroxysmal dyskinesia’ (PD) describes a manifestation of involuntary movement or muscle tone, which by definition is episodic in nature and self-limiting. The PDs remain poorly understood and frequently under-recognised conditions in veterinary patients. The purpose of this article is to review the basic classification and principles of recognition and diagnosis of PDs. This article introduces some of the breed-specific PDs, as well as the treatment/management options available and expected outcomes.

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Dyskinesia Associated with Oral Phenobarbital Administration in a Dog

Cited by 27 publications

References 9 publications

Canine Paroxysmal Movement Disorders

Canine Paroxysmal Movement Disorders

International veterinary epilepsy task force consensus proposal: outcome of therapeutic interventions in canine and feline epilepsy

Approach to canine paroxysmal dyskinesias

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