Dysgonic fermenter-2: A clinico-epidemiologic review

Job, Leela; Horman, Joseph T.; Grigor, Jack K.; Israel, Ebenezer

doi:10.1016/0736-4679(89)90268-0

Cited by 17 publications

(5 citation statements)

References 53 publications

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“…Septic shock following animal bites in asplenic or cirrhotic patients, with a clinical picture reminiscent of meningococcal septicaemia with purpura fulminans, malar purpura, is a classical presentation of Capnocytophaga canimorsus (Dysgonic Fermenter type 2/DF2) infection. 18,19 Mortality is 40%. 20 The diagnosis is confirmed easily by examining a peripheral blood film (preferably a buffy coat) for organisms.…”

Section: Laboratory Testsmentioning

confidence: 99%

Hospital management of animal and human bites

Matt¹

2005

Journal of Hospital Infection

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Section: Laboratory Testsmentioning

confidence: 99%

Hospital management of animal and human bites

Matt¹

2005

Journal of Hospital Infection

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“…In spite of the numerous antibiotics to which C. canimorsus is susceptible in vitro, penicillin G is recommended as the drug of choice [81], because most pathogens which may be present in bite wound are susceptible to this antibiotic. Many authors use amoxicillin/clavulanic acid [82], since additionaly Staphylococci and anaerobes are sensitive.…”

Section: Bacteriologymentioning

confidence: 99%

Capnocytophaga canimorsus infections in human: Review of the literature and cases report

1996

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Capnocytophaga canimorsus, formerly designated Dysgonic fermenter 2 (DF-2) was first described in 1976; it is a commensal bacterium of dogs and cats saliva, which can be transmitted to man by bite (54% of cases), scratch (8.5%), or mere exposure to animals (27%). We present a review of the clinical and microbiological characteristics of the Capnocytophaga canimorsus infections and 12 cases of infection in France. Over 100 cases of human infections have been reported, mainly septicemia in patients with diminished defences, due to splenectomy (33%), alcohol abuse (24%), immunosuppression (5%). However 40% of septicemia occur in patients with no predisposing conditions. Other infections are less frequent: meningitis, endocarditis, arthritis, pleural and localized eye infections. These infections range from mild to fulminating disease, with shock, respiratory distress, disseminated intravascular coagulation. Dermatological lesions (macular or maculopapular rash, purpura) or gangrene are common. This fastidious Gram-negative bacterium grows slowly on chocolate agar or on heart infusion agar with 5% rabbit blood incubated in 5% CO2. In spite of a great susceptibility of bacteria to antibiotics, the mortality is of 30%. Because of the severity of these infections, taking into account this organism in the management of bites is necessary, especially in patients with predisposing factors.

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“…Rabies is a possibility when a dog bite is sustained abroad or from a quarantined dog. Capnocytophaga canimorsus (previously known as dysgonic fermenter-2; DF-2) is a Gram-negative bacillus that can, rarely, contaminate dog (or cat) bites and may give rise to a rapidly progressive and potentially fatal sepsis syndrome, especially in people who are immunocompromised 3 , 18 , 19…”

Section: Features Of Bites From Mammalsmentioning

confidence: 99%

Managing bites from humans and other mammals

2004

DTB

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Dysgonic fermenter-2: A clinico-epidemiologic review

Cited by 17 publications

References 53 publications

Hospital management of animal and human bites

Hospital management of animal and human bites

Capnocytophaga canimorsus infections in human: Review of the literature and cases report

Managing bites from humans and other mammals

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