Dyscrasias With “Undetermined Significance”

A Potential Pathogenic Role for Aberrant DNA Rearrangements in Bridging Dyscrasias of Undetermined Significance and Lymphoma?

“…Diet, or more precisely, the chemicals in the diet have been shown to act as ligands for transcription factor receptors, to serve as signaling molecules, and to be metabolized by primary or secondary metabolic pathways thereby altering concentrations of substrates or intermediates. 1 Kaput and coauthor, R. L. Rodriguez (director of the Center of Excellence for Nutritional Genomics at the University of California, Davis), 2 summarize the new science of nutrigenomics as follows:…”

“…Through these metabolic substrates and chemoattractant agents, M phaseolina spores provide a niche for P fluorescens in the soil. 1 An analogous relationship between P aeruginosa and fungal nail pathogens may exist. In spite of the apparent growthpromoting effects exerted by fungal species on P aeruginosa, fungi are in turn rendered less viable in vitro by these bacteria.…”