Dysbiosis and Predicted Functions of the Dental Biofilm of Dairy Goats with Periodontitis

Borsanelli, Ana Carolina; Athayde, Flávia Regina Florencio de; Saraiva, Júlia Rebecca; Riggio, Marcello P.; Dutra, Iveraldo S.

doi:10.1007/s00248-022-02062-0

Cited by 7 publications

(8 citation statements)

References 62 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, the Gram-negative genera Bacteroides, Fusobacterium and Porphyromonas were the most abundant in the microbiota of deer abscesses. These genera have also been identified in great abundance in the oral microbiota of kangaroos with progressive periodontal disease (Yip et al 2021) and in domestic ruminants such as cattle, sheep and goats with periodontitis (Borsanelli et al 2018(Borsanelli et al , 2021(Borsanelli et al , 2022b(Borsanelli et al , 2022c. Some members of Fusobacterium genus can connect with different microorganisms, acting as a bridge between early colonizers and the latter periodontopathogens, including anaerobic Gram-negative like Bacteroides and Porphyromonas (Li et al 2015).…”

Section: Discussionmentioning

confidence: 99%

“…Black-pigmented anaerobes belonging to Porphyromonas genus represent the most prevalent microorganisms in the microbiota of cattle, sheep, and goats with periodontitis and are associated with the disease in these animals (Borsanelli et al 2021(Borsanelli et al , 2022b(Borsanelli et al , 2022c. These microorganisms can express potent virulence factors and interfere with the host's innate immune response (Haffajee & Socransky 1994).…”

Section: Discussionmentioning

confidence: 99%

“…The richness and diversity of the dental microbiome of ruminants in health and diseased phenotypes (Borsanelli et al 2018(Borsanelli et al , 2021(Borsanelli et al , 2022b(Borsanelli et al , 2022c suggest a robust source of possibilities and risks in orofacial infections. Of this predominantly strict anaerobic microbiota, there are several opportunistic bacteria with invasive capacity, including aerobic or facultative microorganisms detected when using only conventional-bacterial culture (Benito-Peña et al 2010, Amorim et al 2011, Rasooli et al 2018.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Fusobacterium necrophorum predominates in the microbiota of mandibular dental abscess in Blastocerus dichotomus

Borsanelli,

Athayde,

Saraiva

et al. 2024

Pesq. Vet. Bras.

Self Cite

View full text Add to dashboard Cite

Dental abscess in ruminants is an acute polymicrobial infection, usually resulting from periodontal disease or endodontic infection, with consequences for animal health and welfare. The present study aimed to describe the bacterial microbiota of dental abscesses in Blastocerus dichotomus. Biological material from mandibular dental abscesses, punctured with a sterile syringe and needle during routine veterinary curative procedures or necropsies, was collected from three ex-situ marsh deer. Bacteria were identified using high-throughput sequencing of the 16S ribosomal RNA gene. The three specimens had the presence of facial bulging, and two died because of severe emaciation with a history of progressive weight loss. Bacteroides (38.6%), Fusobacterium (36.65%), and Porphyromonas (7.49%) represented the most abundant genera and Fusobacterium necrophorum (35.69%), Porphyromonas levii (3.12%) and Porphyromonas gulae (1.78%) were among the ten most represented species in the microbiota of mandibular abscess in Blastocerus dichotomus. These molecular findings demonstrate a broader diversity of species in the polymicrobial nature of dental abscesses in B. dichotomus than was previously reported when culture-dependent methods were used in the diagnosis.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Fusobacterium necrophorum predominates in the microbiota of mandibular dental abscess in Blastocerus dichotomus

Borsanelli,

Athayde,

Saraiva

et al. 2024

Pesq. Vet. Bras.

Self Cite

View full text Add to dashboard Cite

show abstract

“…9 Next-generation sequencing studies of dental biofilm in ruminants have shown that specific groups of microorganisms are involved in healthy and diseased phenotypes. [9][10][11] Periodontal diseases in ruminants may be influenced by various environmental, dietary and modifying factors and have a seasonal pattern. These diseases have a progressive and cumulative evolution, with successive episodes of exacerbation and remission of their precursor forms.…”

Section: Introductionmentioning

confidence: 99%

“…Periodontitis is a complex set of polymicrobial and synergistic immunoinflammatory diseases that are associated with dysbiosis of the microbiota in the dental biofilm of sheep 9 . Next‐generation sequencing studies of dental biofilm in ruminants have shown that specific groups of microorganisms are involved in healthy and diseased phenotypes 9–11 …”

Section: Introductionmentioning

confidence: 99%

Co‐occurrence of periodontal lesions and dental wear in incisor and masticatory teeth in two sheep flocks in Brazil

Agostinho,

Borsanelli,

Campello

et al. 2023

Veterinary Record

Self Cite

View full text Add to dashboard Cite

BackgroundPeriodontitis and tooth wear are multifactorial diseases with distinct etiopathogenesis that affect the health, feed efficiency and welfare of sheep.MethodsThis study evaluated the co‐occurrence of tooth wear and periodontal lesions in 129 ewes from two Brazilian flocks, clinically classified the lesions and presence of dental calculus, and identified potential pathogens in the dental biofilm of 63 ewes by polymerase chain reaction.ResultsOf the 129 ewes included in the study, 75 presented periodontal lesions, while all animals presented tooth wear and dental calculus. Of the animals with periodontal lesions, 16.2% had lesions in incisor teeth and 52.7% in masticatory teeth. Regarding excessive tooth wear, 38.6% had severe wear on the incisor teeth and 89.1% on the masticatory teeth. Ewes older than 36 months had a higher frequency of periodontal lesions in incisor teeth (p < 0.001) and a greater amount of dental calculus (p < 0.001), but there was no association between tooth wear and animal age. Fusobacterium nucleatum, Tannerella forsythia and Fusobacterium necrophorum predominated in periodontal lesions.LimitationThis study is limited by the small sample size and lack of diagnostic imaging to assess periodontal disease.ConclusionThe co‐occurrence of periodontal lesions and excessive dental wear involving both the incisor and masticatory teeth suggests that although the two diseases have different aetiologies, they likely have common risk factors.

show abstract

Gingivitis in cattle and supplemental protein diet: Insights from proteomic analysis

Saraiva

Dionízio

Borsanelli

et al. 2023

Journal of Proteomics

View full text Add to dashboard Cite

Dysbiosis and Predicted Functions of the Dental Biofilm of Dairy Goats with Periodontitis

Cited by 7 publications

References 62 publications

Fusobacterium necrophorum predominates in the microbiota of mandibular dental abscess in Blastocerus dichotomus

Fusobacterium necrophorum predominates in the microbiota of mandibular dental abscess in Blastocerus dichotomus

Co‐occurrence of periodontal lesions and dental wear in incisor and masticatory teeth in two sheep flocks in Brazil

Gingivitis in cattle and supplemental protein diet: Insights from proteomic analysis

Contact Info

Product

Resources

About