Dynamics of spermatogenesis, hormonal and immune response of patients suffering from chronic prostatitis and sterility under bitemporal treatment with an ultra-high frequency electric field

Abstract

A new method of treatment of patients with chronic prostatitis and sterility by means of ultra-high frequency (60 W) electric field applied bitemporally has been proposed. During treatment 82% of the patients showed an increase in the number of spermatozoa in 1 ml of ejaculate; the percentage of movable and morphologically normal spermatozoa has increased. Patients with chronic prostatitis and sterility showed in the prostatic secrete before treatment a predominance of B-lymphocytes over T-lymphocytes. After treatment the number of T-lymphocytes in the prostatic secrete increased and the content of B-lymphocytes decreased. In the subpopulation of T-lymphocytes the content of T-suppressors increased, the content of T-helpers and O-lymphocytes decreased. At the same time patients with sterility showed an increase in blood testosterone level and an FSH decrease. Out of 67 wives of the patients with sterility 50 reported pregnancy within 6 months after beginning of the treatment.

Prostatitis and male factor infertility: A review of the literature

“…A negative impact of estrogen may be concluded from a study in which treatment with the estrogen-lowering drug mepartricin in CPPS resulted in a reduction of pelvic pain and improved quality-of-life scores compared with the placebo group [42]. Furthermore, there is indirect evidence from older studies that patients with chronic nonbacterial prostatitis may have reduced seminal and circulating testosterone levels [43][44][45].…”

Prostatitis versus pelvic pain syndrome: Immunologic studies

“…Furthermore, the elevated oxidative stress observed in seminal plasma [17,83] has been related to infertility in these patients [84]. In EPS of patients with chronic prostatitis and sterility, a predominance of B-over T-lymphocytes was reported; however, after successful treatment, the number of T cells (and especially the T suppressor cells) increased [85].…”

Prostatitis versus pelvic pain syndrome: Immunologic studies

“…The involvement of immunologic pathways may be evidenced by the detection of increased levels of antisperm antibodies in these patients compared with control subjects [80,81], possibly leading to reduced sperm motility in Category III patients [82]. In EPS of patients with chronic prostatitis and sterility, a predominance of B-over T-lymphocytes was reported; however, after successful treatment, the number of T cells (and especially the T suppressor cells) increased [85]. In EPS of patients with chronic prostatitis and sterility, a predominance of B-over T-lymphocytes was reported; however, after successful treatment, the number of T cells (and especially the T suppressor cells) increased [85].…”