Dynamics of serum C-reactive protein (CRP) level and cosmophysical activity

Stoupel, E.; Abramson, Evgeny; Israelevich, P. L.; Sulkes, Jaqueline; Harell, Daniella

doi:10.1016/j.ejim.2006.09.010

Cited by 28 publications

(21 citation statements)

References 18 publications

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“…Some differences and adverse response to those changes by different subsets of IHD and CVA can explain the generally sober links of those two groups to the studied physical parameters: different groups of fatal events are responding in a different way to changing physical environment. There are some examples: such important "acute phase" messengers like fibrinogen, C-reactive protein, many blood coagulation ingredients predisposing to thrombosis, are higher in high GMA days (26,44). In addition, arterial pressure shows such trend.…”

Section: Discussionmentioning

confidence: 99%

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Clinical cosmobiology: distribution of deaths during 180 months and cosmophysical activity. The Lithuanian study, 1990–2004 The role of cosmic rays

et al. 2007

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Section: Discussionmentioning

confidence: 99%

“…The number of ischemic stroke-related deaths is rising (26). We mentioned analogical changes for prolactin and 17-ketosteroids (31,(41)(42)(43)(44)(45)(46)(47). It is also remarkable that stormy days of GMA are relatively rare -in the last 30 years, in the middle latitudes, 3.5-6.0% of days yearly (47).…”

Section: Discussionmentioning

confidence: 99%

Clinical cosmobiology: distribution of deaths during 180 months and cosmophysical activity. The Lithuanian study, 1990–2004 The role of cosmic rays

et al. 2007

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“…[26] In addition, some of risk factors of Coronary Heart Disease like arterial pressure, blood lipids and coagulation, C-reactive protein (CRP), life threatening cardiac arrhythmia (ventricular fibrillation, tachycardia), atrial fibrillation, cardiac arrhythmia in patients with AMI were studied in relation to accompanying levels of GMA, CRA, SA, Space Proton flux of different energy levels. [1][2][3][4][5][6][7][8][9][26][27][28][29][30][31][32].…”

Section: Discussionmentioning

confidence: 99%

“…These symptoms can be short, resulting in angina pectoris attacks (AP), and longer and more severe, but remaining without significant myocardial damage named Intermediate Coronary Syndrome (ICS) The drop of blood supply and provoked oxygen and other vital agents disballance for a longer time (mostly more than 20 minutes) often lead to necrobiosis in the area of the damaged (culprit) artery with a specific additional complex of symptoms:(clinical, electrocardiographic, enzymatic) and result in later scar formation, or myocardial rupture, life threatening arrhythmias, aneurysm formation, heart failure that is considered as Acute myocardial Infarction (AMI).The ICS takes place between AP and AMI. Recent studied demonstrated significant links between a number of pathogenetic factors involved in ACS development and environmental physical activity [1][2][3][4][5][6][7][8][9]. The aim of this study was to explore AMI and ICS (code I21-I22 versus I20, ICD 10) by differences in concomitant environmental physical conditions: Geomagnetic, Solar and Cosmic Ray (Neutron) activity.…”

Section: Introductionmentioning

confidence: 99%

Acute Myocardial Infarction (AMI) and Intermediate Coronary Syndrome (ICS)

Stoupel¹,

Tamoshiunas²,

Radishauskas³

et al. 2010

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In recent studies it was shown that blood coagulation and inflammation markers are raising at high geomagnetic activity; acute myocardial infarction and all his subtypes, mostly related to atheromatous plaque disruption with higher Cosmic Ray (Neutron) activity. The aim of this study was to explore AMI and ICS differences by concomitant physical conditions, accompanying each of these acute coronary syndromes. (r=0.23, p=0.048). ICS was not correlated with these two parameters, but show significant links to GMA (r=0.25, p=0.037). Gender differences were evident, men more close related to changes in the mentioned physical parameters.Conclusion: 1. Monthly number of AMI and ICS is different related to fluctuations of environmental physical parameters. 2. The described connections can affect differences in the pathogenesis of these forms of Acute Coronary Insufficiency.

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“…In these studies some medical events were significantly and inversely related with the level of GMA. Such results were seen for SCD in a number of studies [15,21,26,27], different forms of cardiac arrhythmia (some forms of them are predictors or components of SCD), also for atrial fibrillation (not only a significant cardiac lesion, but a major risk factor for stroke) [31][32][33][34][35][36]. In a number of following observations also significant links were seen for total number of AMI and its different subtypes (STEMI, NSTEMI, Q-wave and non-Q-wave AMI) [21,35].…”

Section: Discussionmentioning

confidence: 99%

Days of “Zero” level geomagnetic activity accompanied by the high neutron activity and dynamics of some medical events—Antipodes to geomagnetic storms

Stoupel¹,

Babayev²,

Abramson³

et al. 2013

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The links of many medical-biological events with high levels of geomagnetic activity (GMA) are widely discussed. In recent years, several medical phenomena were described in inverse distribution by time with GMA. Also a concurrent to GMA and solar activity force-cosmic ray activity (CRA) and closely related high energy neutron and proton fluxes are studied as a forces dominating at low GMA and solar activity in relation to considered medical events. The aim of this study was to explore the distribution of some important medical events on days with "Zero" GMA levels, accompanied by high CRA (neutron activity). Medical event data of the Grand Baku region (more than 3 mln inhabitants), Azerbaijan, with daily distribution on the time 1 Dec. 2002-31 Dec. 2007 was compared to daily GMA Kp indices in general (Kp > 0, 1837 days) and 34 days daily GMA indices Kp = 0. Daily CRA data was also compared using neutron monitoring data from two stations. Daily averaged data and their standard deviations on the mentioned GMA levels were compared and statistical significance was established. Results revealed a significant rise in the number of emergencies (n = 1,567,576) and total deaths number (n = 46,360) at the days of "Zero" GMA level. These days were accompanied by significant rise of CRA (neutron activity). For Sudden Cardiac Deaths (SCD, n = 1615) and cerebral stroke (CVA, n =10,054) the increase achieved strong trend to significance level. Acute Myocardial Infarction occurrence (morbidity) and trauma were also absolutely more registered at days with "Zero" GMA level, despite the small number of such days. The average Infection numbers show an inverse relationship with absolutely high registry at the "Zero" GMA level days. Study linking environmental physical activity levels and the human medical data shows that geomagnetic field variations accompanied by the increased level of cosmic ray activity, can have either direct or indirect adverse effects on human health and physiology, even when the magnitude of the geomagnetic field disturbance is extremely small or even is equal to zero. On days of "Zero" daily Kp indices describing Geomagnetic Activity, accompanied by high Cosmic Ray Activity (neutron activity), more medical emergencies and total death number (daily) occurred. Sudden Cardiac Deaths and Cerebral Stroke numbers show a strong trend to significant rise. Absolute increase of number of Acute Myocardial Infarction and less Infections, not achieving statistical significance, was also observed. These results are additional data for considering Cosmic Ray Activity (neutron activity) as an additional factor involved in time distribution of human medical events.

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Dynamics of serum C-reactive protein (CRP) level and cosmophysical activity

Cited by 28 publications

References 18 publications

Clinical cosmobiology: distribution of deaths during 180 months and cosmophysical activity. The Lithuanian study, 1990–2004 The role of cosmic rays

Clinical cosmobiology: distribution of deaths during 180 months and cosmophysical activity. The Lithuanian study, 1990–2004 The role of cosmic rays

Acute Myocardial Infarction (AMI) and Intermediate Coronary Syndrome (ICS)

Days of “Zero” level geomagnetic activity accompanied by the high neutron activity and dynamics of some medical events—Antipodes to geomagnetic storms

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