Dynamics of Quality of Life Indices in Case of Metabolic Syndrome
in Patients with Paranoid Schizophrenia on the Background
of Atypical Neuroleptic Agents Application and Improvement
of Comorbidity

Romash, Ivan; Vynnyk, Mykhailo I

doi:10.36927/2079-0325-v27-is4-2019-11

Cited by 7 publications

(2 citation statements)

References 5 publications

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“…As a result, this leads to negative consequences in their physical and psychological state such as deterioration in health, well-being, mood, and performance; and weakening of cognitive functions. The signs of psycho-physiological and psycho-emotional disorders such as chronic stress, anxiety, grumpiness, depression, fatigue, low activity, reduced performance, and violations in the social sphere appear (Romash, 2019;2020). These disorders are called "winter-over syndrome".…”

Section: Introductionmentioning

confidence: 99%

Main features of expeditioners’personality traits in Antarctic conditions

Bakhmutova

2021

MHGCJ

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Introduction. Determining the benefits of basic human personality traits is one of the main components of the selection and staffing of small groups of peoples that are working in extreme environmental conditions and socio-spatial isolation. These groups include teams of polar explorers, scientists from outlying research bases, ship and submarine crews, and aircraft and space shuttles teams. Purpose. To identify the prevailing type of temperament of and personal changes in people working on the Antarctic station during a one-year period of isolation to develop measures to maintain their mental and physical health. Methodology. A total of 48 people (46 men and 2 women aged from 23 to 63 years) from four wintering teams of the Ukrainian Antarctic station (UAS) “Akademik Vernadsky” were voluntarily interviewed according to the Eysenck Personality Questionnaire (EPQ). The poll was conducted twice – before the departure to the Antarctic station and after their return after a year. Participants were studied in two groups (24 peoples) once again after a 6-month stay on the Antarctic station, to determine the level of psychoticism. The research was based on the analysis of preferences and changes in personality traits: Extraversion/Introversion, Neuroticism/Stability, and Psychoticism/Socialization. Results. Based on the analysis of indicators such as Extraversion/Introversion, Neuroticism/Stability, and Psychoticism/Socialization, we determined the general structure of the personal characteristics of the expeditioners. Indicators of these characteristics showed that more than a third of the expeditioners (36.1%) were pronounced extroverts. A majority (61.1%) of the respondents were characterized by an intermediate between extraversion and introversion, and only 2.8% were pronounced introverts. 58.4% of the respondents were characterized by a low level of neuroticism, while 33.3% were characterized by medium level of neuroticism. Only 8.3% were found to have a high level of neuroticism. Low levels of psychoticism were predominant in 56.3% of the respondents while the remaining 43.7% had medium levels of psychoticism. A high level of psychoticism was absent in the respondents which indicates a psychologically correct selection of the team. Analysis of the dynamics of psychoticism revealed that there were higher growth rates (+0.97) of average indexes of psychoticism during the first 6 months of the expeditioners’ stay at the Antarctic station than at the end of the activity. This was due to the “acute adaptation” period when the respondent fit in the natural conditions of Antarctica. Furthermore, there was a development of psychoticism in the expeditioners during the “polar night”; the growth rates of psychoticism decreased after adaptation. Conclusions. To maintain people’s mental health at the Antarctic station, it is optimal to select candidates for a one-year expedition with average rates of extraversion-introversion, and mostly low rates of neuroticism and psychoticism. These personal characteristics must be taken into account when forming an expedition team. The level of psychoticism during the expedition increases under the influence of the adverse environmental conditions of Antarctica and the socio-spatial isolation

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Section: Introductionmentioning

confidence: 99%

Main features of expeditioners’personality traits in Antarctic conditions

Bakhmutova

2021

MHGCJ

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“…Regarding the life expectancy, it is, on average, 10 years shorter (by 30% according to other estimates) in patients with schizophrenia. After conducting a comprehensive analysis of scientific researches, scientists have concluded that patients with schizophrenia have a higher prevalence of cardiovascular disease, obesity, diabetes, osteoporosis in comparison with the general population [11]. Such comorbid somatic diseases in case of schizophrenia have a more acute course, a significant impact on the course of the underlying disease, the development of complications.…”

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Assessment of comorbid profile, quality of life and social functioning in patients with schizophrenia and schizotypal disorders

Romash

2023

Med. perspekt.

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One of the most common mental illnesses is schizophrenia and schizotypal disorders. According to the literature data, mortality among patients with schizophrenia is 1.5-2 times higher than among the general population. Patients with schizophrenia have a higher prevalence of cardiovascular disease, obesity, diabetes, osteoporosis in comparison with the general population. Such comorbid somatic diseases in the case of schizophrenia have a more acute course, a significant impact on the course of the underlying disease, the development of complications, decrease in quality of life and social functioning. The aim of the study was to study the presence and features of comorbidity, its impact on the quality of life and social functioning of patients with schizophrenia and schizotypal disorders. 100 patients were included in the study. They were divided into two groups: experimental (Group I) with schizophrenia and comparison (Group II), with other schizophrenic diseases, such as schizoaffective and schizotypal disorder. All patients were scaled according to the following methods: The Cumulative Illness Rating Scale (CIRS), Clinical Global Impression – Severity Scale (CGI-S), The Personal Social Performance Scale (PSP), CGI-S, and a short form of the questionnaire Medical Outcomes Study 36-Item Short-Form Health Status (SF-36). Charlson Index was also calculated for all patients included in the study. Due to CIRS, we detected undiagnosed comorbidity that aggravated the course of the underlying disease: 38% in Group I and 26% in Group II. The most common components in the structure of comorbidity in the patients with schizophrenia were diabetes mellitus, musculoskeletal diseases, cardiovascular diseases, non-alcoholic fatty liver disease (NAFLD). Patients with schizotypal disorders were more often diagnosed with peripheral vascular diseases, chronic lung diseases, chronic kidney diseases, and upper gastrointestinal tract disorders. A comprehensive approach to be important in the treatment of such patients. The nature and extent of comorbidity should be definitely taken into account. This will promote the compliance and improve the indicators in the examined category of patients.

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Dynamics of quality of life indicators in patients with gastroesophageal reflux disease comorbid with connective tissue dysplasia under the influence of complex treatment

Romash

2021

MHGCJ

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Introduction. In the case of gastroesophageal reflux disease (GERD) on the background of undifferentiated connective tissue dysplasia (UCTD) causes an even more significant deterioration in the QOL, including sleep disturbances and the onset of excessive daytime sleepiness (EDS). Thus, the study of the peculiarities of GERD on the background of connective tissue dysplasia and determining the impact of comorbid pathology on the QOL of patients with GERD is a topical issue in internal medicine. It has significant socio-economic significance. We believe that monitoring the most important variables that affect the quality of life of patients with GERD can help raise public awareness in this regard. In addition, it can guide the health care system to address these issues. Purpose. The purpose of the work is to increase the awareness of medical workers about the scale of the problem and ways to solve it. to study the features of the dynamics of quality of life in patients with gastroesophageal reflux disease comorbid with connective tissue dysplasia under the influence of the proposed complex therapy. Methodology. 120 patients were included: 65 men and 55 women. In 75 of them (Study Group) GERD was in the background of UCTD, in 45 (?omparison Group ) - developed as an independent disease. The Study Group was divided into three groups. ?omparison Group - 45 patients with GERD without UCTD, received basic standard therapy, which included PPI "Panocid" 40 mg once a day and alginate-antacid formulation (Gaviscon Double Action Liquid) 20 ml, 3 times per day after meals and before bedtime. I Group - 25 patients with GERD +UCTD, which to the standard basic therapy was added "Magne-B6" for 2 tablets 3 times per day. II Group - 25 patients with GERD +UCTD, which to the standard basic therapy was added "Calcium-D3 Nicomed" 1 tablet 3 times per day. III Group - 25 patients with GERD +UCTD, who used the drug "Magne-B6" 2 tablets 3 times per day and "Calcium-D3 Nicomed" 1 tablet 3 times per day on the background of standard basic therapy. The Medical Outcomes Study 36-Item Short-Form Health Status (SF-36), the Gastrointestinal Symptom Rating Scale (GSRS), and the scale of "Personal and social performance" (PSP) - were used to study patients in detail. A comprehensive examination of patients was performed twice: before and after 30 days of comprehensive treatment. Results and Discussion. Under the influence of the basic therapy in Comparison Group the General Health (GH) improved by 33.03%. While in the groups on the background of complex treatment is increased by 42.52% in patients of the I Group, by 13.10% in patients of the II Group, and 46.28% in patients of the III Group (p1, p2, p3 <0.05).Physical Functiong Scale (PF) improved by 17.9% in patients of the Comparison Group (p <0.05) and by 30.38%; 27.47%, 29.17%, respectively (p1, p2, p3 <0.05). Role Physical Scale (RP) scores improved by 25.14% in Comparison Group (p <0.05) and by 33.6 %, 22.58% and 40.20% respectively (p1, p2, p3 <0.05). Dynamics of data in Body Pain (BP) scale improved by 21.84% in patients of the Comparison Group (p <0.05) and by 37.28%, 25.46%, 35.92% (p1, p2, p3 <0.05).As can be seen from it, under the influence of complex therapy, the values of the Vitality (VT) increased by 17.18% in patients of Group I, by 21.93% – in Group II, by 37.87%– in Group III (p1, p2, p3 <0.05). Among patients of the Comparison Group, the influx of strength and energy felt 9.50% (p <0.05). Data of Social Functioning Scale (SF) improved by 8.8% in patients of the Comparison Group (p <0 , 05) and by 22.7%, 29.6%, 29.31%, respectively(p1, p2, p3 <0.05). Mental Health Scale (MH) improved by 17.23% in patients of Group I, by 22.41% – in Group II, by 21.96% – in Group III (p1, p2, p3 <0.05) and 14.22% - in the Comparison Group (p <0.05). Also in patients were positive dynamics of the Role Emotional functioning scale (RE): by 27.37% in patients of Group I, by 12.36%– in Group II, by 15.7% – in the Group III (p1, p2, p3 <0.05) and 9.05% - in patients of the Comparison Group (p < 0.05). Conclusions. Thus, the inclusion in the standard therapy of gastroesophageal reflux disease in patients with its development on the background of undifferentiated connective tissue dysplasia of magnesium lactate dihydrate in combination with pyridoxine hydrochloride ("Magne -B6 ") and calcium carbonate in combination with cholecalciferol ("Calcium-D3 Nicomed") contributed to a significant improvement in their quality of life

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Dynamics of Quality of Life Indices in Case of Metabolic Syndrome in Patients with Paranoid Schizophrenia on the Background of Atypical Neuroleptic Agents Application and Improvement of Comorbidity

Cited by 7 publications

References 5 publications

Main features of expeditioners’personality traits in Antarctic conditions

Main features of expeditioners’personality traits in Antarctic conditions

Assessment of comorbid profile, quality of life and social functioning in patients with schizophrenia and schizotypal disorders

Dynamics of quality of life indicators in patients with gastroesophageal reflux disease comorbid with connective tissue dysplasia under the influence of complex treatment

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