Dynamics of Inflammatory Parameters After Endovascular and Open Infrarenal Abdominal Aneurysm Repair

Abstract

Background: The aim of this paper was to investigate the dynamics of inflammatory parameters in patients after infrarenal abdominal aneurysm surgery.Methods: The retrospective study included patients with operated infrarenalabdominal aneurysm, divided into two groups. First group were patients that underwent endovascular aneurysm repair procedure (EVAR), and second group were patients that had open surgery. General data and inflammatory parameters (CRP, leukocytes, platelets, and fibrinogen) had been taken during hospitalization, compared mutually and analyzed.Main findings:All inflammatory parameters, observed preoperatively, were close to referent range. Serum CRP values in EVAR patients raised after operation, but returned to the reference range more quickly as well as leukocyte count. Around the middle of their own hospital stay and at the day of discharge, the group operated on by the open method had statistically significant higher platelet values than the EVAR group. During the preoperative period and in the middle of hospitalization, the group operated on by the open method shows higher fibrinogen values, while the opposite is at the day of discharge, where the EVAR group shows statistically significantly higher fibrinogen values.Principal conclusions: Observed serum inflammatory parameters (CRP, leukocytes, fibrinogen, and platelets) in different phases of hospitalization were lower; closer to the reference value in patients with infrarenal abdominal aneurysm that underwent EVAR, compared to patients operated by the open surgery method. Also, the observed parameters, except fibrinogen, returned to the reference value faster in patients who underwent EVAR.Key words: abdominal aortic aneurysm, endovascular aneurysm repair, inflammatory parameters