“…The latter explanation seems plausible, especially in a view of the apparent, albeit weak, negative association between the severity and the duration of symptoms. Change of R out has been seen to occur with time in post‐subarachnoid haemorrhage hydrocephalus (16) and with increasing age (12). It is possible that changes in R out and other physiological parameters do also occur in patients with iNPH.…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, CSF compensatory parameters are known to change with time in some conditions (14). For example, R out increases shortly after the SAH, with a tendency to settle down a few weeks later (15, 16).…”
This is a preliminary observation, and it suggests that for patients with duration of symptoms longer than 2-3 years, the threshold for normal resistance to CSF outflow should be duration-adjusted.
“…The latter explanation seems plausible, especially in a view of the apparent, albeit weak, negative association between the severity and the duration of symptoms. Change of R out has been seen to occur with time in post‐subarachnoid haemorrhage hydrocephalus (16) and with increasing age (12). It is possible that changes in R out and other physiological parameters do also occur in patients with iNPH.…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, CSF compensatory parameters are known to change with time in some conditions (14). For example, R out increases shortly after the SAH, with a tendency to settle down a few weeks later (15, 16).…”
This is a preliminary observation, and it suggests that for patients with duration of symptoms longer than 2-3 years, the threshold for normal resistance to CSF outflow should be duration-adjusted.
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