2023
DOI: 10.1161/circep.123.011914
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Dynamics of High-Density Unipolar Epicardial Electrograms During PFA

Abstract: BACKGROUND: Pulsed field ablation (PFA) is a novel nonthermal cardiac ablation technology based on irreversible electroporation (IRE). While areas of IRE lead to durable lesions, the surrounding regions, where reversible electroporation occurs, recover. The behavior of local electrograms in areas of different electroporation levels remains unknown. The goal of this study is to characterize electrogram dynamics after PFA in IRE and reversible electroporation areas. … Show more

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Cited by 3 publications
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“…We believe that the ability to distinguish irreversible from reversible changes related to PFA will be extremely important as PFA is increasingly used. In this regard, Amorós-Figueras et al 15 offer a detailed and important assessment of reversible versus irreversible effects of PFA by looking at unipolar electrogram and make an important addition to the existing literature. 16 They carefully delineate the dynamic unipolar electrogram changes after PFA and compare changes that occur at the center, border, and periphery of the lesions using a high-density electrode matrix (128 microelectrodes with an interelectrode space of 0.75 mm) positioned around the site of application.…”
Section: Editorialmentioning
confidence: 99%
“…We believe that the ability to distinguish irreversible from reversible changes related to PFA will be extremely important as PFA is increasingly used. In this regard, Amorós-Figueras et al 15 offer a detailed and important assessment of reversible versus irreversible effects of PFA by looking at unipolar electrogram and make an important addition to the existing literature. 16 They carefully delineate the dynamic unipolar electrogram changes after PFA and compare changes that occur at the center, border, and periphery of the lesions using a high-density electrode matrix (128 microelectrodes with an interelectrode space of 0.75 mm) positioned around the site of application.…”
Section: Editorialmentioning
confidence: 99%