“…41 These issues led to the development of the hyperintensity on post-treatment FLAIR imaging, relative to baseline, are correlated with improved survival. 35 Furthermore, some glioblastomas demonstrate imaging changes consistent with progression under the Macdonald criteria, but upon repeat surgical intervention, viable tumor cannot be identified in the resection specimen, suggesting that the adjuvant treatment may actually be having a positive effect that eludes detection on conventional imaging. This finding, termed "pseudoprogression," Axial post-contrast T1 (T1CE) images at 8 months.…”