Dynamics of external ocular blood flow studied by scanning angiographic microscopy

Ld, Ormerod; Fariza, Enrique; Rh, Webb

doi:10.1038/eye.1995.148

Cited by 11 publications

(5 citation statements)

References 28 publications

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“…These measures, made through a scanner laser ophthalmoscopy (SLO) require injection of a contrast agent (151, 152). SLO coupled with adaptive optics (153) and optical coherence tomography angiography (OCT-A) allow for the measurement of all the retinal layers and accurately visualize both retinal and choroidal microvasculature without contrast agent injection (154, 155).…”

Section: Methods For Measuring Pulsatility In the Microvasculaturementioning

confidence: 99%

Measuring the Interaction Between the Macro- and Micro-Vasculature

Climie

Gallo

Picone

et al. 2019

Front. Cardiovasc. Med.

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Structural and functional dysfunction in both the macro- and microvasculature are a feature of essential hypertension. In a healthy cardiovascular system, the elastic properties of the large arteries ensure that pulsations in pressure and flow generated by cyclic left ventricular contraction are dampened, so that less pulsatile pressure and flow are delivered at the microvascular level. However, in response to aging, hypertension, and other disease states, arterial stiffening limits the buffering capacity of the elastic arteries, thus exposing the microvasculature to increased pulsatile stress. This is thought to be particularly pertinent to high flow/low resistance organs such as the brain and kidney, which may be sensitive to excess pressure and flow pulsatility, damaging capillary networks, and resulting in target organ damage. In this review, we describe the clinical relevance of the pulsatile interaction between the macro- and microvasculature and summarize current methods for measuring the transmission of pulsatility between the two sites.

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Section: Methods For Measuring Pulsatility In the Microvasculaturementioning

confidence: 99%

Measuring the Interaction Between the Macro- and Micro-Vasculature

Climie

Gallo

Picone

et al. 2019

Front. Cardiovasc. Med.

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“…He had an extensive history of vascular disease with severe carotid artery stenosis; the left, ipsilateral to both the nonarteritic ischemic optic neuropathy and conjunctival-corneal melt, being totally occluded. Antecubital-episcleral perfusion times were markedly delayed on fluorescein angiography (normal 8–23 seconds depending on height [Ormerod et al 1995]), again, more so to the left. In the absence of other risk factors for conjunctival-corneal melt this cannot be ignored.…”

Section: Discussionmentioning

confidence: 99%

Conjunctival-corneal melt in association with carotid artery stenosis

Stewart

Quah²,

Nguyen³

et al. 2008

OPTH

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PurposeTo report a case of severe conjunctival-corneal melt in association with carotid artery stenosis.MethodsObservational case report.ResultsA 76-year-old man with a history of bilateral severe carotid artery occlusion and nonarteritic ischemic optic neuropathy developed a spontaneous bulbar conjunctival defect. Despite intensive lubrication, and attempts at surgical closure including an amniotic membrane patch graft, it progressed with subsequent adjacent corneal perforation. Thorough investigations revealed no underlying disease, except markedly delayed episcleral vessel filling on anterior segment fluorescein angiography.ConclusionsNeovascularisation is a known factor in the inhibition of ulceration. In light of the findings in this report, ocular ischemia should be considered as a cause or contributing factor in the differential diagnosis of conjunctival-corneal melt.

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“…Meyer [70] on angiography of 13 subjects found the incidence of arteries lowest over the lateral rectus muscle. Ormerod et al [71]. found marked individual variability and much larger vertical ACAs.…”

Section: Anatomy Of the Anterior Ciliary Arteriesmentioning

confidence: 95%

“…The ciliary body consists of 3 parts: pars plana, pars plicata and ciliary muscle [65]. Leber [9] described an intramuscular arterial circle in the ciliary body, which has been confirmed by others in primates [98,99] as well in the human [71]. This circle is formed by anastomoses between the perforating branches of the ACAs and LPCAs in the ciliary muscle.…”

Section: Blood Supply Of the Ciliary Bodymentioning

confidence: 99%

Uveal vascular bed in health and disease: uveal vascular bed anatomy. Paper 1 of 2

Hayreh

Hayreh²

2023

Eye

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The uveal vascular bed is the largest vascular system in the eye and has a role in supplying almost every tissue in the eyeball. This makes it the most important ocular vascular system. This is an up-to-date review of the literature of the entire uveal vascular bed in health based on detailed anatomy of the posterior ciliary arteries (PCAs), anterior ciliary arteries, cilioretinal arteries, and vortex veins. Although postmortem injection cast preparations gave us useful information on the morphology of the choroidal vascular bed; in vivo studies showed that they misled us for centuries about the in vivo situation. According to the postmortem cast studies, the uveal vascular bed has no segmental distribution, the uveal vessels anastomose freely with one another, there are inter-arterial and arteriovenous anastomoses in the choroid, and the choriocapillaris form a freely communicating and an uninterrupted vascular bed in the entire choroid.

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Dynamics of external ocular blood flow studied by scanning angiographic microscopy

Cited by 11 publications

References 28 publications

Measuring the Interaction Between the Macro- and Micro-Vasculature

Measuring the Interaction Between the Macro- and Micro-Vasculature

Conjunctival-corneal melt in association with carotid artery stenosis

Uveal vascular bed in health and disease: uveal vascular bed anatomy. Paper 1 of 2

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