Dynamics of changes in population immunity to the SARS-CоV-2 virus in residents the Irkutsk region in the context of the COVID-19 pandemic

Балахонов, С. В.; Дубровина, В. И.; Pyatidesyatnikova, A. B.; Брюхова, Д. Д.; Киселева, Н. О.; Korytov, K. M.; Войткова, В. В.; Пережогин, А. Н.; Chesnokova, M. V.; Гаврилова, Т. А.; Seledtsov, A. A.

doi:10.31631/2073-3046-2021-20-2-12-17

Cited by 8 publications

(1 citation statement)

References 10 publications

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“…Достаточно большое количество статей (5,6%) посвящено состоянию популяционного иммунитета к вирусу SARS-CoV-2. В рамках широкомасштабного проекта Роспотребнадзора были пред-ставлены сероэпидемиологических исследований населения Нижегородской, Иркутской, Новосибирской областей, Ставропольского и Красноярского краев и Дальнего Востока [17][18][19][20][21][22].…”

Section: Key Messages What Is Already Known About the Subject?unclassified

Russian-language publication activity of medical researchers in during the COVID-19 pandemic: “post-COVID-19 syndrome”

Kim¹,

Drapkina²,

Rodionova³

2022

Cardiovasc Ther Prev

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Aim. To study the dynamics and pattern of publications in Russian on post-COVID-19 syndrome (PCS) in order to assess the completeness of information and identify medical specialties with its most active investigation in Russia.Material and methods. The search for publications was carried out in the database of the largest digital scientific library in Russia Elibrary.ru from February 1, 2021 to February 1, 2022. The study included publicly available medical publications on the consequences of coronavirus disease 2019 (COVID-19) in Russian. Publications were classified according to subject matter, study design, and evidence hierarchy. The data obtained is reflected using integers, percentages and graphs.Results. The study included 478 publications, of which 196 (41%) presented data from original studies, while 269 (56,3%) reflected the results of existing sources. Expert community documents accounted for 2,7%. In terms of study design, most of original studies described case series (37,2%) and individual case reports (22,4%). Casecontrol studies accounted for 20,4%, cross-sectional studies — 8,7%, prospective cohort studies — 3,6%, randomized clinical trials — 1,5%, and systematic reviews — 1%. In addition, 5,1% of publications were devoted to preclinical studies, mathematical models and various methodological aspects. By topic, the largest number of publications noted cardiovascular (12,2%) and neurological manifestations of PCS (12,2%). Furthermore, 23,5% of publications described the course of PCS in specific groups of patients, particular issues of COVID-19 consequences, and healthcare management problems. We also revealed that 11,7% of publications were devoted to general rehabilitation, 71% — to imaging diagnostics, 5,6% — to herd immunity to the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARSCoV-2), and 5,6% — to PCS features in children. The smallest number of publications considered mental (5,1%), gastroenterological (4,6%), pharmacological (4,6%), rheumatological (4%) and pulmonological aspects of PCS.Conclusion. The dynamics and pattern of publications on COVID-19 in Russian are generally consistent with global trends and reflect the natural consequences of the pandemic. This analysis of publications on PCS showed that the most in-demand specializations in this filed are cardiology, neurology, and rehabilitation.

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Section: Key Messages What Is Already Known About the Subject?unclassified

Russian-language publication activity of medical researchers in during the COVID-19 pandemic: “post-COVID-19 syndrome”

Kim¹,

Drapkina²,

Rodionova³

2022

Cardiovasc Ther Prev

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Calculation of epidemic thresholds for incidence of community-acquired pneumonia

Ботвинкин

Кравченко

Bayanova

et al. 2022

Fundamentalʹnaâ i kliničeskaâ medicina

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Aim. To calculate epidemic incidence thresholds for community-acquired pneumonia in the Irkutsk Region and to identify irregularities in the annual incidence trends.Materials and Methods. We carried out a cross-sectional epidemiological study evaluating the relevant data from the Irkutsk Region during 2013-2020. To calculate the epidemic thresholds, we used weekly information for 2013-2018 about newly diagnosed cases of community-acquired pneumonia. Similar data for 2019 and 2020 were used for retrospective comparison with the calculated thresholds.Results. Computation of the community-acquired pneumonia epidemic incidence thresholds is based on the weekly and 4-week calculation of the median and quartiles (Q1 ; Q3 ), which is conducted differentially for the total population, children (≤ 17 years of age), working adults (18-64 years of age) and pensioners (≥ 65 years of age) per 100,000 population. When compared with the upper epidemic threshold (Q3 ), seasonal changes in the incidence of community-acquired pneumonia have been revealed in 2019 and 2020; they were associated with the spread of infuenza, COVID-19, and an epidemic of unknown origin which was observed mostly among children.Conclusion. Calculation of epidemic thresholds for the incidence of community-acquired pneumonia can be used in epidemiological surveillance.

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Assessment of Population Immunity to the Sars-Cov-2 Virus Among the Population of Grodno

Krotkova¹,

Кузнецов²,

Harchakova³

2021

Journal GrSMU

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In Grodno, as well as in the Republic of Belarus as a whole, vaccination of the population against COVID-19 infection is being actively carried out. Purpose of the study: To assess population immunity to the SARS-CoV-2 virus among the population of the city of Grodno. The material of the study was the blood sera of 422 patients, residents of Grodno. Results. Among the studied subjects 32.7% (n=138) of cases had the level of class G antibodies to the receptor-binding domain (RBD) of the S protein (hereinafter RBD of the S protein) which was higher than 1.1 units of the positivity coefficient. A high seropositivity index (40.4%) was established among people who had not previously been infected with COVID-19 and were vaccinated with Sputnik V, the lowest – in the group of people who had not been infected with the infection and were not vaccinated – 25%. The assessment of the antibodies concentration adjusted for the age of the subjects did not reveal significant changes in their level. As regards the time interval, it was found that those individuals, who were vaccinated with Sputnik V vaccine regardless of whether they had been ill or not with COVID-19 infection before, had the highest level of antibodies within the second month after the last dose of the vaccine, which decreased by the fourth month after vaccination and remained at this level for up to six months.

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Dynamics of changes in population immunity to the SARS-CоV-2 virus in residents the Irkutsk region in the context of the COVID-19 pandemic

Cited by 8 publications

References 10 publications

Russian-language publication activity of medical researchers in during the COVID-19 pandemic: “post-COVID-19 syndrome”

Russian-language publication activity of medical researchers in during the COVID-19 pandemic: “post-COVID-19 syndrome”

Calculation of epidemic thresholds for incidence of community-acquired pneumonia

Assessment of Population Immunity to the Sars-Cov-2 Virus Among the Population of Grodno

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