Dynamics of cardiorespiratory response during and after the six-minute walk test in patients with heart failure

Yoshimura, Kosuke; Urabe, Yukio; Maeda, Noriaki; Yuguchi, Satoshi; Yoshida, Toshinobu

doi:10.1080/09593985.2018.1489925

Cited by 9 publications

(12 citation statements)

References 43 publications

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“…18 A high VE/VCO 2 slope, an important prognostic marker in patients with HF, derived from CPET, 4,41 has been inversely associated with 6MWD. 4,50 On the other hand, in a randomized trial, in older patients with HF with preserved ejection fraction, 6MWD did not correlate with measures obtained from CPET and thus its usefulness as a test of functional capacity in this population has been challenged. 53…”

Section: Mwt In Populations With Hfmentioning

confidence: 99%

“…It has been previously shown that CPET parameters such as VO 2 peak, VO 2 max and anaerobic threshold are the best indicators of functional capacity in patients with HF. 4,41 Several studies have shown moderate-to-strong correlations of 6MWD with peak aerobic capacity (peak VO 2 ) in CPET in HF populations (Table 2); 2,4,7,10,13,18,42–51 in patients with HF being evaluated for transplantation, a 6MWD < 350 m has a sensitivity of 71% and specificity of 60% for predicting VO 2 max <14 ml/kg/min. 5,52 Maximal power output during the CPET was found to be also independently associated with 6MWD.…”

Section: Mwt In Populations With Hfmentioning

confidence: 99%

See 1 more Smart Citation

6-minute walking test: a useful tool in the management of heart failure patients

Giannitsi

Bougiakli

Bechlioulis

et al. 2019

Therapeutic Advances in Cardiovascular Disease

180

141

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Reduced functional ability and exercise tolerance in patients with heart failure (HF) are associated with poor quality of life and a worse prognosis. The 6-minute walking test (6MWT) is a widely available and well-tolerated test for the assessment of the functional capacity of patients with HF. Although the cardiopulmonary exercise test (a maximal exercise test) remains the gold standard for the evaluation of exercise capacity in patients with HF, the 6MWT (submaximal exercise test) may provide reliable information about the patient’s daily activity. The current review summarizes the value of 6MWT in patients with HF and identifies its usefulness and limitations in everyday clinical practice in populations of HF. We aimed to investigate potential associations of 6MWD with other measures of functional status and determinants of 6MWD in patients with HF as well as to review its prognostic role and changes to various interventions in these patients.

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Section: Mwt In Populations With Hfmentioning

confidence: 99%

Section: Mwt In Populations With Hfmentioning

confidence: 99%

6-minute walking test: a useful tool in the management of heart failure patients

Giannitsi

Bougiakli

Bechlioulis

et al. 2019

Therapeutic Advances in Cardiovascular Disease

180

141

View full text Add to dashboard Cite

show abstract

“…For the patients over 40 years of age, a HR limit of 130 beats/min and a MET level of five are often used. The submaximal test is fit for hospitalized patients and maximal utilizing gas exchange is used to evaluate congestive heart failure and timing for heart transplantation [27–30].…”

Section: Exercise-induced Stress Tests For Patient Cvd Risk Assessmentmentioning

confidence: 99%

“…The maximal test is most commonly used and appropriate for general individual. Both Submaximal and Maximal EST are generally performed on a treadmill [27–30].…”

Section: Exercise-induced Stress Tests For Patient Cvd Risk Assessmentmentioning

confidence: 99%

A systematic comparison of exercise training protocols on animal models of cardiovascular capacity

Feng

Wang

et al. 2019

Life Sciences

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Cardiovascular disease (CVD) is a major global cause of mortality, which has prompted numerous studies seeking to reduce the risk of heart failure and sudden cardiac death. While regular physical activity is known to improve CVD associated morbidity and mortality, the optimal duration, frequency, and intensity of exercise remains unclear. To address this uncertainty, various animal models have been used to study the cardioprotective effects of exercise and related molecular mechanism such as the mice training models significantly decrease size of myocardial infarct by affecting Kir6.1, VSMC sarc-KATP channels, and pulmonary eNOS. Although these findings cement the importance of animal models in studying exercise induced cardioprotection, the vast assortment of exercise protocols makes comparison across studies difficult. To address this issue, we review and break down the existent exercise models into categories based on exercise modality, intensity, frequency, and duration. The timing of sample collection is also compared and sorted into four distinct phases: pre-exercise (Phase I), mid-exercise (Phase II), exercise recovery (Phase III), and post-exercise (Phase IV). Finally, because the life-span of animals so are limited, small changes in animal exercise duration can corresponded to untenable amounts of human exercise. To address this limitation, we introduce the Life-Span Relative Exercise Time (RETlife span) as a method of accurately defining short-term, medium-term and long-term exercise relative to the animal’s life expectancy. Systematic organization of existent protocols and this new system of defining exercise duration will allow for a more solid framework from which researchers can extrapolate animal model data to clinical application.

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“…Both respiratory rate and TV have been studied as indicators of the anaerobic threshold [2], [3], which is related to the fitness level. The assessment of the fitness level results interesting for heart failure patients [4] and for athletes. Respiration monitoring techniques are usually based on plethysmography, pneumography or spirometry.…”

mentioning

confidence: 99%

Electrocardiogram-Derived Tidal Volume During Treadmill Stress Test

Milagro

Hernando

Lázaro

et al. 2020

IEEE Trans. Biomed. Eng.

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Objective: Electrocardiogram (ECG) has been regarded as a source of respiratory information with the main focus in the estimation of the respiratory rate. Although little research concerning the estimation of tidal volume (TV) has been conducted, there are several ECG-derived features that have been related with TV in the literature, such as ECG-derived respiration, heart rate variability or respiratory rate. In this work, we exploited these features for estimating TV using a linear model. Methods: 25 young (33.4 ± 5.2 years) healthy male volunteers were recruited for performing a maximal (MaxT) and a submaximal (SubT) treadmill stress test, which were conducted in different days. Both tests were automatically segmented in stages attending to the heart rate. Afterwards, a subject-specific TV model was calibrated for each stage, employing features from MaxT, and the model was later used for estimating the TV in SubT. Results: During exercise, the different proposed approaches led to relative fitting errors lower than 14% in most of the cases and than 6% in some of them. Conclusion: Low achieved fitting errors suggest that TV can be estimated from ECG during a treadmill stress test. Significance: The results suggest that it is possible to estimate TV during exercise using only ECG-derived features.

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Dynamics of cardiorespiratory response during and after the six-minute walk test in patients with heart failure

Abstract: In lower exercise capacity patients with HF had slower [Formula: see text]O and [Formula: see text]E kinetics during and after the 6MWT.

Cited by 9 publications

References 43 publications

6-minute walking test: a useful tool in the management of heart failure patients

6-minute walking test: a useful tool in the management of heart failure patients

A systematic comparison of exercise training protocols on animal models of cardiovascular capacity

Electrocardiogram-Derived Tidal Volume During Treadmill Stress Test

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