Dynamic Stereochemistry and Chiroptical Spectroscopy of Metallo‐Organic Compounds

Conformational changes and chiroptical switching of enantiopure bis-helicenic terpyridine upon Zn2+ binding

“…The contribution of chiroptical molecular switches 1 to the field of functional devices is stimulated by many potential applications such as molecular information processing, data storage, or probes for the detection of chirality. 2 Interconversion between two or more stable chiral forms can result from responses of chiral molecules to external stimuli such as heat, light, pressure, solvent, pH, change in redox potential or presence of chemicals.…”

Chiroptical Switches: Applications in Sensing and Catalysis

“…Holmes and Balaz at al recently used unbridged achiral anionic nickel(II) meso-tetra(4-sulfonatophenyl) porphyrin for the highly sensitive and specific chiroptical detection of condensed left-handed Z-DNA in the presence of canonical right-handed B-DNA [ 37 ]. Other chiroptical sensors [ 20 , 38 , 39 , 40 ] for chiral guests have also been recently reviewed [ 13 , 14 , 41 ].…”

“…Many metal ion-induced switches have been reported [ 45 , 46 , 47 , 48 , 49 ] and reviewed [ 11 , 13 , 14 ]. Recently, two multi-mode Hg(II) sensors, L-MethBQA and L-CysBQA ( Figure 6 ) [ 44 ], were obtained by fusing methionine or S -methyl cysteine, into a bis-quinolyl amine based chiral podand scaffold.…”

“…This review will mainly cover chiroptical switches that are used as senors and/or catalysts and will be organized by stimuli input mechanism. More extensive coverage on chiroptical switches can be found in other review articles [ 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 ].…”

“…Chiroptical spectroscopic measurements are powerful tools for the characterization of materials and outcomes in these fields, and may include any form of polarized light measurement [ 16 ]. A recent book chapter [ 13 ] on metal-base dynamic stereochemical systems is organized by their chiroptical responses: Optical rotation [ 17 ], ORD [ 18 ], ECD, VCD [ 19 ], FDCD/CPE and CPL [ 20 ]. We provide brief explanations of the chiroptical spectroscopic terms used in this paper in the assessment of chiroptical switches as listed in Table 1 .…”