Dynamic overdrive pacing for the suppression of ventricular ectopic activity: long-term application using implantable pacemakers

Winter, U. J.; Behrenbeck, D. W.; Höher, Martin; Brill, Th.; H, Ebeling; Hirche, Hj.; Hilger, H. H.

doi:10.1007/978-94-009-4293-6_43

Cited by 1 publication

(2 citation statements)

References 18 publications

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“…Therefore, in a subset of cardiac patients, where bradycardia exacerbates arrhythmia, rate acceleration can decrease PVC frequency by making refractoriness more uniform, thereby reducing the likelihood of re-entry. This is similar to dynamic overdrive pacing that has been used for short-term suppression of ventricular ectopic activity [14].…”

Section: Discussionmentioning

confidence: 98%

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Sustained Suppression of Premature Ventricular Contractions by a Three-Month Pacing Adjustment

Sackin¹,

Campbell²,

Werth³

et al. 2022

Cureus

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Premature ventricular contractions (PVCs) that comprise more than 15% of total heartbeats can induce cardiomyopathy in patients with systolic dysfunction, and cardiac ablation is frequently used to reduce PVCs in this patient group. However, cardiac ablation is not entirely without hazards. We report a noninvasive method that dramatically reduced premature ventricular contractions (PVC) in a cardiac pacemaker patient from 31% to 3% in 7 days by increasing the lower limit pacing rate from 50 bpm to 60 bpm. Not only were our patient's PVCs reduced by the initial pacing elevation, but PVC levels were maintained below 5% even after the pacemaker's lower limit was returned to its original value of 50 bpm. This irreversible suppression of PVC activity following a 3-month pacing elevation is a novel result that might be caused by ventricular remodeling of the original ectopic focus.

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Section: Discussionmentioning

confidence: 98%

“…Pacing rate adjustment as a strategy for PVC reduction is nothing new [8,13,14]. In hypothermic dogs, ectopic beats occurred more frequently at 50 bpm but decreased as HR was raised, with complete abolition at 75 bpm pacing [15].…”

Section: Discussionmentioning

confidence: 99%