Dynamic Myocardial Perfusion CT for the Detection of Hemodynamically Significant Coronary Artery Disease

Nous, Fay; Geisler, Tobias; Kruk, Mariusz; Alkadhi, Hatem; Kitagawa, Kakuya; Vliegenthart, Rozemarijn; Hell, Michaela M.; Hausleiter, Jörg; Nguyen, Patricia K.; Budde, Ricardo P.J.; Nikolaou, Konstantin; Kępka, Cezary; Manka, Robert; Sakuma, Hajime; Malik, Sachin B.; Coenen, Adriaan; Zijlstra, Felix; Klotz, Ernst; Harst, Pim van der; Artzner, Christoph; Dedic, Admir; Pugliese, Francesca; Bamberg, Fabian; Nieman, Koen

doi:10.1016/j.jcmg.2021.07.021

Cited by 49 publications

(29 citation statements)

References 31 publications

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“…CT-MPI is an emerging modality which combines anatomic imaging with additional functional information by detecting pharmacologic hyperemia from the myocardial enhancement patterns after injection of contrast medium to quantify MBF. This has advantages in patients with dense calcifications or in whom the functional impact of a stenotic lesion is uncertain, its widespread use has been limited, however, due to its relative complexity and increased radiation exposure [ 72 ]. CT-fractional flow reserve (CT-FFR) is a more available, emerging modality which can reduce the false positive rate associated with CCTA by reclassifying lesions by their hemodynamic significance.…”

Section: Discussionmentioning

confidence: 99%

Multimodality Imaging in the Detection of Ischemic Heart Disease in Women

Gaine

Sharma

Tower‐Rader

et al. 2022

JCDD

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Women with coronary artery disease tend to have a worse short and long-term prognosis relative to men and the incidence of atherosclerotic cardiovascular disease is increasing. Women are less likely to present with classic anginal symptoms when compared with men and more likely to be misdiagnosed. Several non-invasive imaging modalities are available for diagnosing ischemic heart disease in women and many of these modalities can also assist with prognostication and help to guide management. Selection of the optimal imaging modality to evaluate women with possible ischemic heart disease is a scenario which clinicians often encounter. Earlier modalities such as exercise treadmill testing demonstrate significant performance variation in men and women, while newer modalities such as coronary CT angiography, myocardial perfusion imaging and cardiac magnetic resonance imaging are highly specific and sensitive for the detection of ischemia and coronary artery disease with greater parity between sexes. Individual factors, availability, diagnostic performance, and female-specific considerations such as pregnancy status may influence the decision to select one modality over another. Emerging techniques such as strain rate imaging, CT-myocardial perfusion imaging and cardiac magnetic resonance imaging present additional options for diagnosing ischemia and coronary microvascular dysfunction.

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Section: Discussionmentioning

confidence: 99%

Multimodality Imaging in the Detection of Ischemic Heart Disease in Women

Gaine

Sharma

Tower‐Rader

et al. 2022

JCDD

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“…The patient in our case report underwent a detailed cardiac evaluation with electrocardiogram, 2D echocardiography, and cardiac CT dynamic study. Cardiac CT is a noninvasive technique that offers several approaches to establish the hemodynamic severity of coronary artery obstructions, demonstrates a good correlation with directly measured coronary flow and fractional flow reserve, 23 and provides incremental diagnostic value over coronary CT angiography alone for the identification of hemodynamically significant coronary artery disease 24 …”

Section: Discussionmentioning

confidence: 99%

Higher pulmonary vein index on computed angiography and optimum surgical resection ensures smooth postoperative recovery in Fallot's tetralogy: Special emphasis on indices of evaluation and Monocusp preparation

Bhende

Sharma

Mehta

et al. 2022

Clinical Case Reports

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“…The patient in our case report underwent a detailed cardiological evaluation with electrocardiogram, 2D echocardiography, and cardiac CT dynamic study. Cardiac CT is a noninvasive technique that offers several approaches to establish the hemodynamic severity of coronary artery obstructions, demonstrates a good correlation with directly measured coronary flow and fractional flow reserve [20], and provides incremental diagnostic value over coronary CT angiography alone for the identification of hemodynamically significant coronary artery disease [21].…”

Section: Discussionmentioning

confidence: 99%

Higher Pulmonary Vein Index From Preoperative Computed Angiography & Good Surgical Resection Ensures A Smooth Post-Operative Recovery Sans Low Cardiac Output Syndrome in a TOF Child-Special Emphasis On Indices Of Evaluation, Monocusp Preparation.

Bhende

SHARMA

Mehta

et al. 2022

Preprint

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Tetralogy of Fallot (TOF) is a common cyanotic congenital heart disease. Its surgical correction requires ventricular septal defect (VSD) closure and right ventricular outflow tract obstruction (RVOTO) relief, with transannular patch enlargement (TAPE) of the pulmonary valve. The first successful repair of TOF was reported in 1954 and consisted of closure of the VSD through a large right ventriculotomy, and RVOTO relief with TAPE of the pulmonary valve. To predict the intra-operative requirements and post-operative course of patients with this condition, various evaluation indices are available that can provide a good indication of patient prognosis. In this case report, we describe a novel pulmonary vein index (PVI) indicator that offers prognostic indications for pediatric cardiac patients who have undergone surgical correction of TOF.

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Dynamic Myocardial Perfusion CT for the Detection of Hemodynamically Significant Coronary Artery Disease

Cited by 49 publications

References 31 publications

Multimodality Imaging in the Detection of Ischemic Heart Disease in Women

Multimodality Imaging in the Detection of Ischemic Heart Disease in Women

Higher pulmonary vein index on computed angiography and optimum surgical resection ensures smooth postoperative recovery in Fallot's tetralogy: Special emphasis on indices of evaluation and Monocusp preparation

Higher Pulmonary Vein Index From Preoperative Computed Angiography & Good Surgical Resection Ensures A Smooth Post-Operative Recovery Sans Low Cardiac Output Syndrome in a TOF Child-Special Emphasis On Indices Of Evaluation, Monocusp Preparation.

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