strategy and as a tool to communicate with attendees and to enable their preparedness, communications, and interactions. Nevertheless for many, effective ICT use is still unclear and inhibitors include inability "to effectively engage audience and monitor active participation" (25%), "to rethink traditional live meeting format" (19%), and "dealing with complex technology issues" (16%)This study examines factors affecting alignment between information and communication technologies (ICTs) strategy and business strategy in professional conference organizers (PCOs). Adopting the resource-based view (RBV), contingency theory, and value discipline theory, a conceptual model is proposed and empirically tested using online survey data. The results indicated that while most PCOs successfully aligned ICTs with business strategies of operational excellence and customer intimacy, very few achieved a tight alignment for product leadership business strategy, found to be the only strategic alignment component significantly impacting on firm performance. Finally, theoretical and practical implications for PCOs' ICTs application are discussed.