Dynamic Interfacial Tension Measurements with Microfluidic Y-Junctions

Steegmans, Maartje L. J.; Warmerdam, Anja; Schroën, Karin; Boom, R.M.

doi:10.1021/la901103r

Cited by 87 publications

(96 citation statements)

References 30 publications

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“…However, when surfactants are present the neck becomes more elongated and "flattened" as it approaches the inner corner of the T junction. Similar observations of neck "stretching" have been noted by other researchers when the interfacial tension is very low in T-junction generators [20,21]. The fatter neck may be caused by interfacial tension gradients on the back half of the droplet because of dilation differences across the interface as the neck collapses.…”

Section: Modification To the Droplet Formation Modelsupporting

confidence: 84%

“…In addition, for each surfactant, the deviation from the model decreases with increasing surfactant concentration. More importantly, these data show that dynamic interfacial effects must always be considered when modeling microfluidic droplet generators, even for a small, fast adsorbing surfactant such as SDS [20,22].…”

Section: Experimental Observationsmentioning

confidence: 94%

“…Adsorption kinetics have also been studied through the measurement of droplet production in microfluidic generators [20][21][22][23]. Wang et al used droplet size, and Nguyen et al used frequency to quantify the dynamic interfacial tension with microfluidic T-junction generators [22,23].…”

Section: Introductionmentioning

confidence: 99%

“…Both of these studies focused on formation times in the millisecond range. Steegmans et al looked at submillisecond effects by analyzing droplet production in a shallow Y-channel design with high flow rates [20]. These studies used semiempirical models to infer the interfacial tension from calibration curves first obtained with pure liquid-liquid combinations.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Droplet formation in microfluidic T-junction generators operating in the transitional regime. III. Dynamic surfactant effects

Glawdel

Ren

2012

Phys. Rev. E

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This study extends our previous work on droplet generation in microfluidic T-junction generators to include dynamic interfacial tension effects created by the presence of surfactants. In Paper I [T. Glawdel, C. Elbuken, and C. L. Ren, Phys. Rev. E 85, 016322 (2012)], we presented experimental findings regarding the formation process in the squeezing-to-transition regime, and in Paper II [T. Glawdel, C. Elbuken, and C. L. Ren, Phys. Rev. E 85, 016323 (2012)] we developed a theoretical model that describes the performance of T-junction generators without surfactants. Here we study dynamic interfacial tension effects for two surfactants, one with a small molecular weight that adsorbs quickly, and the other with a large molecular weight that adsorbs slowly. Using the force balance developed in Paper II we extract the dynamic interfacial tension from high speed videos obtained during experiments. We then develop a theoretical model to predict the dynamic interfacial tension in microfluidic T-junction generators as a function of the surfactant properties, flow conditions, and generator design. This model is then incorporated into the overall model for generator performance to effectively predict the size of droplets produced when surfactants are present.

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Section: Modification To the Droplet Formation Modelsupporting

confidence: 84%

Section: Experimental Observationsmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Droplet formation in microfluidic T-junction generators operating in the transitional regime. III. Dynamic surfactant effects

Glawdel

Ren

2012

Phys. Rev. E

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“…28 Recently, microfluidic devices with distinctive advantages, including small sample volume, high sensitivity, and point of care feasibility, have been introduced to effectively manipulate small amounts of fluids in microfluidic channels for biomedical applications. For example, several microfluidic platforms have been applied to measure fluid properties such as surface tension, 29,30 density, [31][32][33] pressure drop, [34][35][36] flow rate, 37,38 and fluid resistance. 39,40 Microfluidic platforms have also been adopted to measure fluid viscosity instead of conventional bulky platforms.…”

mentioning

confidence: 99%

Label-free viscosity measurement of complex fluids using reversal flow switching manipulation in a microfluidic channel

2013

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The accurate viscosity measurement of complex fluids is essential for characterizing fluidic behaviors in blood vessels and in microfluidic channels of lab-on-a-chip devices. A microfluidic platform that accurately identifies biophysical properties of blood can be used as a promising tool for the early detections of cardiovascular and microcirculation diseases. In this study, a flowswitching phenomenon depending on hydrodynamic balancing in a microfluidic channel was adopted to conduct viscosity measurement of complex fluids with label-free operation. A microfluidic device for demonstrating this proposed method was designed to have two inlets for supplying the test and reference fluids, two side channels in parallel, and a junction channel connected to the midpoint of the two side channels. According to this proposed method, viscosities of various fluids with different phases (aqueous, oil, and blood) in relation to that of reference fluid were accurately determined by measuring the switching flow-rate ratio between the test and reference fluids, when a reverse flow of the test or reference fluid occurs in the junction channel. An analytical viscosity formula was derived to measure the viscosity of a test fluid in relation to that of the corresponding reference fluid using a discrete circuit model for the microfluidic device. The experimental analysis for evaluating the effects of various parameters on the performance of the proposed method revealed that the fluidic resistance ratio (R JL /R L , fluidic resistance in the junction channel (R JL ) to fluidic resistance in the side channel (R L )) strongly affects the measurement accuracy. The microfluidic device with smaller R JL /R L values is helpful to measure accurately the viscosity of the test fluid. The proposed method accurately measured the viscosities of various fluids, including single-phase (Glycerin and plasma) and oil-water phase (oil vs. deionized water) fluids, compared with conventional methods. The proposed method was also successfully applied to measure viscosities of blood with varying hematocrits, chemically fixed RBC S , and channel sizes. Based on these experimental results, the proposed method can be effectively used to measure the viscosities of various fluids easily, without any fluorescent labeling and tedious calibration procedures.

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Study on the transient interfacial tension in a microfluidic droplet formation coupling interphase mass transfer process

et al. 2016

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In two-phase dispersion coupling interphase mass transfer process, the variation of interfacial tension is an important factor affecting the dispersion. In this study, we described a microfluidic method for the determination of the transient interfacial tension (TIFT). The method has the advantage of determining TIFT during the whole droplet formation process, rather than only at the rupture moment as reported in previous studies. The TIFTs of several systems were determined. In certain systems, it has been found that the droplet size decreased with the increase of the dispersed phase flow rate, which is obviously different from the constant interfacial tension system. It has also been found that TIFT was mainly affected by two-phase flow rates, solute type and concentration, and droplet size. A semiempirical equation was finally established to predict TIFT. It has the potential to be used in a variety of industrial equipment with dispersionmass transfer coupling process.

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Dynamic Interfacial Tension Measurements with Microfluidic Y-Junctions

Cited by 87 publications

References 30 publications

Droplet formation in microfluidic T-junction generators operating in the transitional regime. III. Dynamic surfactant effects

Droplet formation in microfluidic T-junction generators operating in the transitional regime. III. Dynamic surfactant effects

Label-free viscosity measurement of complex fluids using reversal flow switching manipulation in a microfluidic channel

Study on the transient interfacial tension in a microfluidic droplet formation coupling interphase mass transfer process

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