Dynamic functional connectivity and gene expression correlates in temporal lobe epilepsy: insights from hidden markov models
Lu Qin,
Qin Zhou,
Yuting Sun
et al.
Abstract:Backgroud
Temporal lobe epilepsy (TLE) is associated with abnormal dynamic functional connectivity patterns, but the dynamic changes in brain activity at each time point remain unclear, as does the potential molecular mechanisms associated with the dynamic temporal characteristics of TLE.
Methods
Resting-state functional magnetic resonance imaging (rs-fMRI) was acquired for 84 TLE patients and 35 healthy controls (HCs). The data was then used to conduct HMM analysis on rs-fMRI data from TLE patients and an H… Show more
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