2020
DOI: 10.21203/rs.3.rs-134799/v1
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Dynamic Flow Priming Programs Allow Tuning Up The Cell Layers Properties for Engineered Vascular Graft.

Abstract: Tissue engineered vascular graft (TEVG) has a good potential to replace and repair demanded blood vessels. Here, we proposed a novel method to create three-layered TEVG on biocompatible glass fiber scaffolds starting from flat sheet state into tubular shape and to train the resulting tissue by our developed bioreactor system. Constructed tubular tissues were matured and trained under 3 types of individual flow programs, and their mechanical and biological properties were analyzed. The strength of scaffold afte… Show more

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