Dynamic Doppler evaluation of the hand arteries of the patients with Raynaud’s disease

Toprak, Uğur; Selvi, Nadir Alper; Ateş, Aşkın; Erhuner, Zeynep; Bostanoğlu, Settar; Karademir, Mehmet Alp; Karaaslan, Yaşar

doi:10.1007/s10067-009-1131-1

Cited by 17 publications

(11 citation statements)

References 6 publications

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“…We have used our clinical protocol, as detailed above, for approximately 3 years [ 3 ]. Toprak et al used 5°C water for cold stimulation in their study and they declared that this temperature is better for provoking the vasospasm than water at 10°C [ 9 ]. Therefore, we routinely used 4°C ice-water for provoking the vasospasm, as in our present study.…”

Section: Discussionmentioning

confidence: 99%

“…In the literature there are few studies about cold stimulation and its effect on ultrasonographic arterial blood flow rates. Most of these studies are focused on the differential diagnosis of the primary form vs. secondary form by using Doppler ultrasonography [ 9 – 11 ]. There have been no studies on its usefulness as a marker of treatment efficacy in the follow-up period.…”

Section: Discussionmentioning

confidence: 99%

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Adding Doppler Ultrasonography to the Follow-Up of Patients with Vasospastic Disorder Improves Objectivity

Karabacak

Kadan

Kaya

et al. 2015

Med Sci Monit Basic Res

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BackgroundAssessing therapeutic efficacy and patient satisfaction objectively and quantitatively has always been a problem in patients with vasospastic disorders. We aimed to present the additive value of ultrasonographic assessment of peripheral arteries secondary to cold stimulation, as a test for treatment efficacy during follow-up.Material/MethodsArterial blood flow rates were measured from radial artery with Doppler USG in patients who presented to our department with vasospastic disorders. Ultrasonography was performed at the following intervals; before cold stimulation and at 5th, 10th, 15th, 20th minutes of cold stimulation. Patients were controlled by repeat cold stimulation test and Doppler US at the 2nd month of the treatment. Results were analyzed with SPSS for Mac 20.0 package program.ResultsWe enrolled 46 patients in the study. All patients were male and mean age was 22.3±2.17 years. Most common symptoms were cyanosis and coldness. There were statistically significant differences between pre-treatment and post-treatment arterial blood flow rates at each measurement time point (p<0.001) except initial measurement (p>0.05). On post-treatment values, there were 10.04±0.78 cm/s increase in 5th minute, 6.25±1.39 cm/s in 10th minute, 6.43±2.13 cm/s in 15th minute, and 6.38±1.86 cm/s in 20th minute measurements. All increases at the 5 time points were statistically meaningful when compared to their pre-treatment corresponding time points (p<0.001).ConclusionsDoppler flowmetry added to standard cold stimulation test for evaluating the patients with vasospastic disorders provides better and more objective results when compared to the patient-oriented subjective scoring systems.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Adding Doppler Ultrasonography to the Follow-Up of Patients with Vasospastic Disorder Improves Objectivity

Karabacak

Kadan

Kaya

et al. 2015

Med Sci Monit Basic Res

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“…15 We evaluated blood flow with a Hadeco Bi-Directional Vascular Doppler®. Measurements were taken according to the protocol described in a previous study 16 where blood flows in radial and ulnar arteries were evaluated in the same way on the volar surface of the wrists of both hands. Result was expressed in cm/s −2 , and the mean of the three measurements was calculated.…”

Section: Methodsmentioning

confidence: 99%

The complementary effects of galvanic current electrical stimulation associated with conservative treatment to increase vasodilation in patients with Raynaud’s phenomenon: a randomized trial

et al. 2020

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Objective: To analyze the effectiveness of an electrotherapy intervention with galvanic current on symptoms associated with Raynaud’s phenomenon. Design: Single-blind randomized controlled trial, parallel design (1:1 ratio) and intention-to-treat analysis. Setting: Virgen de las Nieves Hospital, Granada, Spain. Subjects: Thirty-four participants with Raynaud’s phenomenon, with a mean (SD) age of 43.43 (17.62) years. Interventions: The patients were randomly assigned to a control group with conservative treatment (anti-inflammatory, vasodilatory and analgesic drugs) or an intervention group that received conservative treatment and vasodilatory electrical stimulation during seven weeks, three times/week for a total of 20 sessions. Main measures: The primary outcome was the number of attacks. Secondary outcomes were pain, peripheral blow flow, oxygen saturation, upper limb disability, central sensitization, pain catastrophizing and temperature recovery. All outcomes were assessed at baseline, posttreatment and at two months of follow-up. Results: The galvanic current electrotherapy group showed significantly greater improvements in the number of attacks (mean difference = 26.3, 95% confidence interval (CI) = 14.4 to 38.3), pre-cold stress pain (95% CI = 0.6 to 2.4), radial artery blood flow (95% CI = −7.8 ⩾ x ⩽ 1.3), ulnar artery blood flow (95% CI = −8.63 to 0.60), oxygen saturation (95% CI = −1.7 ⩾ x ⩽ −0.29), upper limb disability (95% CI = 1.1 to 22.3), central sensitization (95% CI = 6.7 to 18.2) and temperature recovery (95% CI = −5.7 ⩾ x ⩽ −0.32) than the conservative treatment group. Conclusion: This study suggests that a complementary treatment with galvanic current in combination to conservative approach is superior to conservative applied as isolate, in reducing the clinical manifestations and disability in Raynaud’s phenomenon.

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“…[1][2][3] The examples include stenosis, thrombosis, embolism, frostbite, traumas, peripheral artery occlusive disease, Raynaud's syndrome, etc. The imaging of microcirculation and capillary networks is useful for the diagnosis of ischemia.…”

Section: Introductionmentioning

confidence: 99%

Optoacoustic angiography of peripheral vasculature

Ermilov

Zamora

et al. 2012

SPIE Proceedings

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We developed a new optoacoustic microangiography system (OmAS) intended for in-vivo vascular imaging of a human finger. The system employs an arc-shaped acoustic array that is rotated 360 degrees around the finger providing optoacoustic data necessary for tomographic reconstruction of the three-dimensional images of a finger. A near-infrared Q-switched laser is used to generate optoacoustic signals with increased contrast of blood vessels. The laser is coupled through two randomized fiberoptic bundles oriented in orthogonal optoacoustic mode. To demonstrate OmAS capabilities, we present a time-series of optoacoustic images of a human finger taken after the hypothermia stress test. The images show a detailed vascular anatomy of a finger down to the capillary level. A series of quick 30s scans allowed us to visualize the thermoregulatory response within the studied finger as it was manifested via vasomotor activity during the hypothermia recovery. We propose that the developed system can be used for diagnostics of various medical conditions that are manifested in change of the peripheral (finger) blood flow. Examples of the medical conditions that could be diagnosed and staged using the OmAS include the peripheral arterial disease (PAD), thrombosis, frostbite, and traumas.

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Dynamic Doppler evaluation of the hand arteries of the patients with Raynaud’s disease

Cited by 17 publications

References 6 publications

Adding Doppler Ultrasonography to the Follow-Up of Patients with Vasospastic Disorder Improves Objectivity

Adding Doppler Ultrasonography to the Follow-Up of Patients with Vasospastic Disorder Improves Objectivity

The complementary effects of galvanic current electrical stimulation associated with conservative treatment to increase vasodilation in patients with Raynaud’s phenomenon: a randomized trial

Optoacoustic angiography of peripheral vasculature

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