Dynamic cyclen–metal complexes for molecular sensing and chirality signaling

Abstract

Structural dynamism plays important roles in artificial and biological systems, because it controls structures and functions of various molecules and assemblies. In this review, molecular recognition and self-assembling behavior of dynamic armed cyclen-metal complexes are discussed at the molecular and supramolecular levels. These metal complexes provide useful platforms for molecular receptors, supramolecules, and molecular assemblies that can respond rapidly to guest molecules and environments. Since armed cyclens have many structural and geometrical variations, they form a wide variety of metal complexes having specific sensing and signaling functions. The Lewis acidity of the metal cations plays an essential role in anion binding and in hydrolytic catalysis of phosphate esters. Characteristic luminescence and magnetic properties of lanthanides also enable techniques for effective bio-imaging. They also serve as chiral building blocks for self-assembled architectures, which offer chirality integration effective for chirality sensing and signaling at the supramolecular level.

Materials‐Based Receptors: Design Principle and Applications

“…Well‐designed receptors show high functionality not only in solution, but also at the interface of self‐assemblies such as lipid membranes and higher aggregates 8. A series of amphiphilic, multiarmedcyclen–metal complexes have been developed, with the construction of highly organized monolayers, vesicles, and related nano‐aggregates 9. Metal complexes with octadentate cyclen ligands typically have quadruple‐stranded helical structures, in which four chiral cholesterol‐functionalized side arms are asymmetrically arranged in a propeller‐like fashion (Figure 2).…”

“…[8] A series of amphiphilic, multiarmedcyclen-metal complexes have been developed, with the construction of highly organized monolayers, vesicles, and related nano-aggregates. [9] Metal complexes with octadentate cyclen ligands typically have quadruple-Abstract: This review focuses on recent developments and growth potential in colorimetric and/or fluorimetric chemosensors based on rationally designed materials and suitable for use in highly selective and sensitive naked-eye detection of environmental and biological analytes. Figure 5.…”

Multifunctional Lanthanide Complexes Based on Tetraazacyclolamidophenol Ligand with Field‐Induced Slow Magnetic Relaxation, Luminescent and SHG Properties

“…Therefore, the small‐molecule lanthanide complex is very suitable for being used as magneto‐luminescent materials . Macrocyclic polyamines, such as 1,4,7,10‐teraazacyclododecane and 1,4,7‐triazacyclononane are fascinating building blocks to synthesize functional chelating ligands in coordination chemistry, which have been successfully utilized in the synthesis of luminescent lanthanide compounds …”

Practical Implementation, Characterization and Applications of a Multi-Colour Time-Gated Luminescence Microscope

“…Autofluorescence in biological samples presents a universal challenge for conventional fluorescence techniques to detect or visualize target species 1 2 3 4 5 6 . The time-gated luminescence (TGL) technique, which takes advantages of long-lived luminescent probes (e.g.…”