Data are presented describing refined simulations of perturbation growth in a three-layer cylindrical liner system tested with disk explosive magnetic flux compression generators (DEMGs) to study the strength properties of copper and polyethylene at shocklessly applied pressures of up to ∼15 GPa. The calculated performance for the same liner system in the experiments to study the strength properties of copper at shockless loading of up to ∼40-GPa pressures is presented. The feasibility of similar strength experiments with quasi-isentropic material compression to ∼2000 GPa using DEMGs is demonstrated.Index Terms-Growth of initial perturbations, magnetic implosion, multilayer liner systems, Rayleigh-Taylor instability, shear strength of materials, strain rate, 2-D computations.