Dynamic Bilateral Contrast-enhanced MR Imaging of the Breast: Trade-off between Spatial and Temporal Resolution

Abstract

Increased spatial resolution significantly improves diagnostic confidence and accuracy at dynamic MR imaging, even if this improvement occurs at the expense of temporal resolution. Loss of kinetic information regarding enhancement rates proved to be not diagnostically relevant because enhancement rates showed broad overlap between benign and malignant lesions and were therefore of only limited diagnostic use in the individual patient. Kinetic information regarding time course pattern was preserved and confirmed as having high specificity and high positive predictive value.

Fast three‐dimensional dual echo dixon technique improves fat suppression in breast MRI

“…As a result, small lesions, particularly subcentimeter lesions, can be obscured or missed. The misregistration artifact can also simulate enhancing lesions (18). In contrast, the fast 3D dual echo Dixon technique used in this study provides high-quality fat suppression that is not subject to patient motion misregistration artifact and is less sensitive to magnetic field inhomogeneity (19).…”

“…In theory, the malignant lesions may be less conspicuous on the Dixon images in this study than the benign lesions because the Dixon images were acquired after the standard axial spectrally selective fat suppressed images. However, the greatest contrast between the slowly enhancing normal fibroglandular tissues and invasive carcinoma is during the first 1 to 3 min after injection (18). Because both sequences being evaluated in this study are acquired after 3 min after injection, both sets of images are at similar disadvantages in demonstrating tissue contrast of invasive carcinoma from the background fibroglandular tissue.…”

Dynamic High-Spatial-Resolution MR Imaging of Invasive Ductal Carcinoma: Influence of Histological Scirrhous Component on MR Descriptors

“…25 However, it is controversial whether the enhancement rate is useful in diŠerentiating benign and malignant lesions. [1][2][3][4][5][6][7]34,35 In this study, T2*-weightedˆrst-pass perfusion data were combined into a high-spatial and high-temporal resolution sequence as a substitute for evaluation of enhancement rates. Based on the results of this study, the potential pitfall of the signiˆcant variability of the signal intensity loss in invasive NOS carcinomas in a T2*-weighted rst-pass perfusion study must be borne in mind.…”

Differentiation between Benign and Malignant Breast Lesions Using ADC on Diffusion-Weighted Imaging at 3.0 T

“…Diffusionweighted imaging (DWI) is the techniques that are performed to increase MRI specificity [7] [8]. The sensitivity of MRI for breast cancer detection ranges from 85% -100% [19] [20], and specificity ranges from only 37% -88% [21] [22]. DWI-MRI is used to detect cancers of the body easily as it has shown that diffusion of the water molecules in malignant tumors is slower compared to the normal body parenchyma.…”